Summary
Myocarditis was experimentally induced in rats by a single intramuscular injection of a large dose of adrenalin (0.5 to 0.8 ml of 1:1000 solution).
Myocardial damage was supported by the data of electrocardiographic and morphological examinations. It was revealed that the rate of inclusion of S35-methionine into the proteins of the cardiac muscle is greatly increased in experimentally-induced myocarditis. This takes place as a result of inclusion of S35-methionine into the muscle fibers as well as into the connective tissue, Its inclusion is especially intensive in places of accumulation of the cellular elements.
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Vedeneeva, Z.I. Effect of massive doses of adrenalin on the protein metabolism of the myocardium of rats. Bull Exp Biol Med 45, 459–464 (1958). https://doi.org/10.1007/BF00781256
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DOI: https://doi.org/10.1007/BF00781256