Receptors of the osmoregulating reflex

Summary

In opposition to E. Verney's (1947) viewpoint that there is a narrow localization of osmoreceptors along a carotis interna in the hypothalamic area, the author assumes that there is a widespread distribution of receptors sensitive to variations of osmotic pressure. This assumption is based on the fact that the antidiuretic reflex, regularly repeated after intracarotid injection of 3% NaCl solution against the background of spontaneous diuresis is absent when urinary excretion is over 5 ml a minute per 1 m² of the body surface. The fact of the wide distribution of osmoreceptors is confirmed by experiments on animals with divided spinal cord in which the depression of the diuretic activity of the kidneys described above occurs with any diuresis.