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A comparative study of the antigenic structure of tumor tissue and homologous normal tissue

Communication II. Investigation of the antigenic properties of Guerin's carcinoma and the normal uterus of the rat by the use of the tissue culture method

  • Oncology
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Bulletin of Experimental Biology and Medicine Aims and scope

Summary

It is possible to detect the antigenic differences between the normal tissue (uterus) and the homologous in origin tumor tissue (Guéren carcinoma) by the method of tissue culture. Such difference consists in the following anticancer serum when adsorbed on the tumour tissue does not possess any cytotoxic effect with respect to the cancer cells, while after adsorption of this serum on the normal tissue of the homologous organ, it begins to inhibit the growth of experimental cultures.

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Literature Cited

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Authors and Affiliations

  1. the Laboratory of Noninfectious Immunology of the Institute of Experimental Biology the AMN SSSR, Moscow

    M. S. Lomakin

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  1. M. S. Lomakin
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Lomakin, M.S. A comparative study of the antigenic structure of tumor tissue and homologous normal tissue. Bull Exp Biol Med 47, 739–744 (1959). https://doi.org/10.1007/BF00781234

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  • DOI: https://doi.org/10.1007/BF00781234

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