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The effect of chlortetracycline on the course of experimental candidomycosis of the lungs in white rats

Communication I. Experiments in which chlortetracycline was injected simultaneously with infection by a cluture of Candida albicans

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

This paper deals with the pathologicoanatomical study of internal organs in 89 white rats infected intranasally withCandida albicans culture. In 50% of the animals tetracycline per os administration was commenced at the day of infection or 2 days prior to it.

This preparation aggravated the course of infection: a) more animals perished in the experimental group than in the control; b) in experimental animals Candida remained in the foci of infection (which, as a rule, were more widespread in this group of animals) for longer periods of time.

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Authors and Affiliations

  1. Pathologicoanatomical Division of the Order of Lenin Naval Hospital, Leningrad

    A. V. Tsinzerling

  2. Laboratory of Infectious Diseases of the Division of Pathological Anatomy of the Institute of Experimental Medicine of the AMN SSSR, Leningrad

    A. V. Tsinzerling

Authors
  1. A. V. Tsinzerling
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Additional information

Given to the Leningrad Scientific Society of Pathologicoanatomists onMarch 25, 1958.

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Tsinzerling, A.V. The effect of chlortetracycline on the course of experimental candidomycosis of the lungs in white rats. Bull Exp Biol Med 47, 685–689 (1959). https://doi.org/10.1007/BF00781220

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  • DOI: https://doi.org/10.1007/BF00781220

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