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Bromocriptine: Pregnancy and progeny

  • Methods for the Synthesis and Production of Therapeutic Agents
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Conclusions

  1. 1.

    Bromocriptine therapy carried out in relation to the genesis of the disease enables the reproductive function of women to be restored and progression of pituitary prolactinomas to be prevented.

  2. 2.

    No nonspecific complications of pregnancy due to the disturbance of prolactin secretion were apparent in a group of patients with hyperprolactinemia treated for a long time with bromocriptine. Conclusive data were obtained on the absence of negative effects on lactation, pregnancy, and birth during the course of the hyperprolactinemia.

  3. 3.

    The data obtained show that neither the character of the hyperprolactinemia nor the form and duration of administration of dopamine agonists had a negative effect on the healthy progeny born to mothers with hyperprolactinemia.

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Literature cited

  1. S. Yu. Kasumova, R. Ya. Snigireva, and V. M. Barabanov, Early Recognition of Endocrine Illnesses: New Methods of Treatment [in Russian], Moscow (1984), pp. 33–34.

  2. I. A. Manuilova and E. I. Sotnikova, Possibility of Medicinal Control of the Hypothalamo-Pituitary System [in Russian], Moscow (1983). pp. 21–26.

  3. T. V. Ovsyannikova, Long-Term Results on the Treatment of Hyperprolactinemia in Women, Author's Summary of Dissertation for Doctor of Medical Sciences, Moscow (1990).

  4. N. V. Speranskaya, T. V. Ovsyannikova, and A. N. Kerova, Probl. Endokrinol., No. 5, 18–23 (1989).

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  5. J. Bergh and S. J. Millius, Fertility and Sterility, Boston (1984), 527–531.

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Translated from Khimiko-farniatsevticheskii Zhurnal, Vol. 27, No. 2, pp. 75–77, February, 1993.

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Ovsyannikova, T.V. Bromocriptine: Pregnancy and progeny. Pharm Chem J 27, 152–154 (1993). https://doi.org/10.1007/BF00781079

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  • DOI: https://doi.org/10.1007/BF00781079

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