Bulletin of Experimental Biology and Medicine

, Volume 47, Issue 1, pp 97–102 | Cite as

Reestablishment of cell division after reactive inhibition by depression of the sympatheticoadrenal system

  • V. V. Kozlov
Experimental Biology


In prolonged stimulation of mice by weak electric current the reactive inhibition of the mitotic activity in the corneal epithelium ceases. However, in 4 hours it reappears notwithstanding the continuing stimulation. Adrenalin administration again depresses the mitosis. If this hormone is administered every 2–3 hours it is possible to inhibit the tissue cells mitosis for hours (even as long as 24 hours). There was no adaptation of cells to adrenalin.

Thus the cause of the reestablishment, of mitotic activity in prolonged action of the current consists in depression of the neurohumoral mechanism responsible for the inhibition of mitosis, mainly of adrenal system.


Public Health Cell Division Adrenalin Electric Current Tissue Cell 
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Copyright information

© Consultants Bureau, Inc. 1959

Authors and Affiliations

  • V. V. Kozlov
    • 1
  1. 1.Department of Histology and Embryology of the I. P. Pavlov First Leningrad Medical InstituteLeningradUSSR

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