Reestablishment of cell division after reactive inhibition by depression of the sympatheticoadrenal system
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In prolonged stimulation of mice by weak electric current the reactive inhibition of the mitotic activity in the corneal epithelium ceases. However, in 4 hours it reappears notwithstanding the continuing stimulation. Adrenalin administration again depresses the mitosis. If this hormone is administered every 2–3 hours it is possible to inhibit the tissue cells mitosis for hours (even as long as 24 hours). There was no adaptation of cells to adrenalin.
Thus the cause of the reestablishment, of mitotic activity in prolonged action of the current consists in depression of the neurohumoral mechanism responsible for the inhibition of mitosis, mainly of adrenal system.
KeywordsPublic Health Cell Division Adrenalin Electric Current Tissue Cell
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