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The Nenitzescu reaction (review)

  • Synthetic Methods and Drug Manufacture Technology
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Literature cited

  1. M. D. Mashkovskii, Drugs [in Russian], Vol. 1, Moscow (1984), pp. 447, 452.

    Google Scholar 

  2. A. N. Grinev, E. K. Panisheva, A. A. Stolyarchuk, and N. I. Ivanova, Khim.-farm. Zh., No. 11, 118–121 (1979).

    Google Scholar 

  3. S. A. Zotova, T. M. Gololobova, A. A. Stolyarchuk, et al., ibid., No. 1, 35–39 (1988).

    Google Scholar 

  4. A. A. Stolyarchuk, N. I. Ivanova, K. S. Shadurskii, et al., Farmakol. Toksikol., No. 3, 292–295 (1970).

    Google Scholar 

  5. V. M. Lyubchanskaya, V. S. Velezheva, I. S. Nikolaeva, et al., Khim.-farm. Zh., No. 7, 843–847 (1989).

    Google Scholar 

  6. S. Arnaise, H. Boeuf, J. P. Buisson, et al., Mutagenesis,1, 217–222 (1986).

    Google Scholar 

  7. R. Royer, Ann. Pharm. Fr.,41, No. 4, 299–311 (1983).

    Google Scholar 

  8. J. P. Buisson, R. Carrier, J. Lemoine, et al., Eur. J. Med. Chem.-Chim. Ther.,10, No. 1, 43–46 (1975).

    Google Scholar 

  9. F. Eiden and U. Kucklander, FRG Patent 2341365 (1975); Chem. Abs.,82, 156071c (1975).

    Google Scholar 

  10. C. Fauran, M. Turin, P. Guerret, et al., French Patent 2242092 (1975); Chem. Abs.,83, 163990a (1975).

    Google Scholar 

  11. U. Kucklander, FRG Patent 2341307 (1975); Chem. Abs.,82, 156071b (1975).

    Google Scholar 

  12. G. R. Allen, Organic Reactions, Vol. 20, New York (1973), 337–455.

    Google Scholar 

  13. R. W. Parr and J. A. Reiss, Aust. J. Chem.,37, No. 6, 1263–1270 (1984).

    Google Scholar 

  14. G. S. Gadaginamath and S. Siddappa, J. Indian Chem. Soc.,52, No. 4, 339–343 (1975).

    Google Scholar 

  15. A. N. Grinev, I. N. Mikhailova, I. S. Nikolaeva, et al., Khim.-farm. Zh., No. 4, 49–54 (1982).

    Google Scholar 

  16. U. Kucklander, Justus Liebigs Ann. Chem., No. 1, 129–139 (1978).

    Google Scholar 

  17. U. Kucklander, ibid., pp. 140–149.

    Google Scholar 

  18. Enamines: Synthesis, Structure, and Reactions, New York-London (1969).

  19. J. Kossakowski, Roczn. Chem.,51, No. 6, 1221–1225 (1977).

    Google Scholar 

  20. U. Kucklander and K. Kuna, Arch. Pharm. (Weinheim, Ger.),322, No. 1, 183–184 (1989).

    Google Scholar 

  21. L. Barries, V. M. Ruiz, R. Tapia, et al., Chem. Lett., No. 2, 187–190 (1980).

    Google Scholar 

  22. C. G. Castro, J. G. Santos, J. C. Valcarcel, et al., J. Org. Chem.,48, No. 18, 3026–3029 (1983).

    Google Scholar 

  23. R. Cassis, R. Tapia, J. A. Valderrama, J. Heterocycl. Chem.,21, No. 3, 869–872 (1984).

    Google Scholar 

  24. E. A. Titov and A. S. Grishchenko, Khim. Geterotsikl. Soedin., No. 7, 872–874 (1972).

    Google Scholar 

  25. E. A. Titov, A. S. Grishchenko, L. A. Gura, and A. N. Kost, ibid., No. 11, 1451–1454 (1973).

    Google Scholar 

  26. N. I. Mikerova and E. K. Panisheva, ibid., No. 10, 1428–1429 (1990).

    Google Scholar 

  27. E. A. Titov and A. S. Grishchenko, Izv. Vyssh. Uchebn. Zaved., Khim. Khim. Tekhnol.,15, No. 2, 239–241 (1972).

    Google Scholar 

  28. A. S. Grishchenko and A. N. Kost, Khim. Geterotsikl. Soedin., No. 4, 490–492 (1976).

    Google Scholar 

  29. V. M. Lyubchanskaya, L. M. Alekseeva, and V. G. Granik, Khim.-farm. Zh., No. 6, 55–56 (1992).

    Google Scholar 

  30. V. M. Lyubchanskaya, L. S. Sarkisova, L. M. Alekseeva, et al., ibid., No. 9–10, 108–112 (1992).

    Google Scholar 

  31. A. N. Grinev, G. Ya. Uretskaya, and S. F. Liberman, Khim. Geterotsikl. Soedin., No. 3, 335–338 (1971).

    Google Scholar 

  32. R. M. Coates and P. A. MacManus, J. Org. Chem.,47, No. 24, 4822–4824 (1982).

    Google Scholar 

  33. V. Polgatti, J. A. Valdarrama, and R. Tapia, Synthetic Commun.,20, No. 8, 1085–1090 (1990).

    Google Scholar 

  34. M. G. Peter and F. Speckenbach, Helv. Chim. Acta,65, No. 4, 1279–1284 (1982).

    Google Scholar 

  35. W. Werner, Arch. Pharm. (Weinheim, Ger.),305, No. 5, 350–353 (1972).

    Google Scholar 

  36. A. N. Grinev, V. I. Shvedov, and E. K. Panisheva, Zh. Org. Khim.,1, No. 11, 2051–2055 (1965).

    Google Scholar 

  37. F. Eiden and U. Kucklander, Arch. Pharm. (Weinheim, Ger.),304, No. 1, 57–64 (1971).

    Google Scholar 

  38. F. Eiden and U. Kucklander, ibid.,306, No. 4, 446–449 (1973).

    Google Scholar 

  39. V. I. Shvedov, E. K. Panisheva, T. F. Vlasova, and A. N. Grinev, Khim. Geterotsikl. Soedin., No. 10, 1354–1356 (1973).

    Google Scholar 

  40. I. Ivanov, L. Raev, and P. Sulai, Farmatsiya (Sofia),34, No. 1, 14–21 (1984).

    Google Scholar 

  41. M. Yokoyama, S. Watanabe, and H. Hatanaka, Synthesis, No. 9, 846–848 (1987).

    Google Scholar 

  42. H. Meerwein, V. Hederich, H. Morschel, and K. Wunderlich, Justus Liebigs Ann. Chem.,635, No. 1, 1–21 (1980).

    Google Scholar 

  43. V. G. Granik, A. M. Zhidkova, and R. G. Glushkov, Usp. Khim.,46, No. 4, 685–711 (1977).

    Google Scholar 

  44. V. G. Granik, Khim. Geterotsikl. Soedin., No. 6, 762–781 (1992).

    Google Scholar 

  45. V. G. Granik, R. G. Glushkov, O. S. Anisimova, et al., Authors Certificate 461930 (1975) USSR; Chem. Abs.,82, 156253 (1975).

  46. V. G. Granik, A. M. Zhidkova, O. S. Anisimova, et al., Khim. Geterotsikl. Soedin., No. 5, 716–717 (1975).

    Google Scholar 

  47. V. M. Lyubchanskaya, V. S. Velezheva, L. M. Alekseeva, et al., ibid., No. 8, 1031–1033 (1989).

    Google Scholar 

  48. J. F. Harris, FRG Patent 2537913 (1976); Chem. Abs.,85, 5483z (1976).

    Google Scholar 

  49. T. I. Mukhanova, L. M. Alekseeva, and V. G. Granik, Khim. Geterotsikl. Soedin., No. 7, 888–891 (1990).

    Google Scholar 

  50. L. Kozerski, Pol. J. Chem.,53, No. 11, 2393–2396 (1979).

    Google Scholar 

  51. Ya. F. Freimanis, Chemistry of Enaminoketones, Enaminoimines, and Enaminothiones [in Russian], Riga (1974), pp. 187–197.

  52. V. G. Granik, Usp. Khim.,53, No. 4, 651–659 (1984).

    Google Scholar 

  53. N. I. Mikerova, N. I. Alekseeva, E. K. Panisheva, et al., Khim. Geterotsikl. Soedin., No. 3, 324–328 (1990).

    Google Scholar 

  54. U. Kucklander, H. Toberich, and K. Kuna, Arch. Pharm. (Weinheim, Ger.),320, No. 4, 308–312 (1987).

    Google Scholar 

  55. U. Kucklander and H. Toberich, ibid., 312–317.

    Google Scholar 

  56. U. Kucklander, H. Toberich, and K. Kuna, ibid.,314, No. 4, 379–380 (1981).

    Google Scholar 

  57. U. Kucklander and H. Toberich, Chem. Ber.,114, No. 6, 2238–2241 (1981).

    Google Scholar 

  58. M. D. Mashkovskii, N. I. Andreeva, and A. I. Polezhaeva, Pharmacology of Antidepressants [in Russian], Moscow (1983), pp. 35–46.

  59. U. Kucklander and H. Toberich, Chem. Ber.,116, No. 1, 152–158 (1983).

    Google Scholar 

  60. U. Kucklander and B. Schneider, ibid.,121, No. 3, 577–579 (1988).

    Google Scholar 

  61. U. Kucklander and B. Schneider, ibid.,119, No. 11, 3487–3491 (1986).

    Google Scholar 

  62. V. Aggrawal, A. Kumar, H. Ila, et al., Synthesis, No. 2, 157–158 (1981).

    Google Scholar 

  63. V. M. Lyubchanskaya, G. S. Chernov, and V. G. Granik, Khim. Geterotsikl. Soedin., No. 5, 704 (1989).

    Google Scholar 

  64. V. M. Lyubchanskaya and V. G. Granik, ibid., No. 5, 597–560 (1990).

    Google Scholar 

  65. R. L. Hinman, Tetrahedron,24, No. 1, 185–190 (1968).

    Google Scholar 

  66. V. G. Granik, S. S. Kiselev, N. P. Solov'eva, et al., Khim. Geterotsikl. Soedin., No. 3, 344–348 (1980).

    Google Scholar 

  67. V. M. Lyubchanskaya, L. M. Alekseeva, and V. G. Granik, ibid., No. 1, 40–45 (1992).

    Google Scholar 

  68. V. M. Lyubchanskaya, L. S. Sarkisova, L. M. Alekseeva, et al., ibid., No. 3, 357–362.

    Google Scholar 

  69. J.-L. Bernier and J.-F. Henichart, J. Org. Chem.,46, No. 21, 4197–4198 (1981).

    Google Scholar 

  70. D. Raileanu, M. Palaghita, and C. D. Nenitzescu, Tetrahedron,27, No. 20, 5031–5047 (1971).

    Google Scholar 

  71. Y. Shvo and H. Shanan-Atidi, J. Am. Chem. Soc.,91, No. 24, 6689–6696 (1969).

    Google Scholar 

  72. N. P. Kostyuchenko, V. G. Granik, A. M. Zhidkova, et al., Khim. Geterotsikl. Soedin., No. 9, 1212–1219 (1974).

    Google Scholar 

  73. U. Kucklander and E. J. Edoho, Arch. Pharm. (Weinheim, Ger.),313, No. 8, 679–683 (1980).

    Google Scholar 

  74. U. Kucklander and E. J. Edoho, ibid., 697–701.

    Google Scholar 

  75. U. Kucklander, Tetrahedron,31, No. 13–14, 1631–1639 (1975).

    Google Scholar 

  76. U. Kucklander, ibid.,28, No. 20, 5251–5259 (1972).

    Google Scholar 

  77. U. Kucklander, Arch. Pharm. (Weinheim, Ger.),310, No. 5, 385–389 (1977).

    Google Scholar 

  78. U. Kucklander, Tetrahedron,29, No. 6, 921–927 (1973).

    Google Scholar 

  79. U. Kucklander and E. J. Edoho, Arch. Pharm. (Weinheim, Ger.),313, No. 7, 582–587 (1980).

    Google Scholar 

  80. L. Kozerski, E. Czerwinska, and T. Pobiedzinska, Tetrahedron,38, No. 5, 617–621 (1982).

    Google Scholar 

  81. U. Kucklander and W. Huhnermann, Arch. Pharm. (Weinheim, Ger.),312, No. 6, 515–526 (1979).

    Google Scholar 

  82. U. Kucklander, P. Ulmer, and G. Zerta, Chem. Ber.,122, No. 8, 1493–1498 (1989).

    Google Scholar 

  83. U. Kucklander, P. Ulmer, K. Kuna, and H. Toberich, ibid., No. 1, 209–212.

    Google Scholar 

  84. M. Palaghita and D. Raileanu, Rev. Roum. Chem.,33, No. 11–12, 953–967 (1988).

    Google Scholar 

  85. J. B. Patrick and E. K. Saunders, Tetrahedron Lett., No. 42, 4009–4012 (1979).

    Google Scholar 

  86. T. I. Mukhanova, L. M. Alekseeva, E. F. Kuleshova, et al., Khim.-farm. Zh., No. 3, 60–65 (1993)

    Google Scholar 

  87. S. S. Kiselev, M. K. Polievktov, and V. G. Granik, Khim. Geterotsikl. Soedin., No. 12, 1678–1682 (1979).

    Google Scholar 

  88. V. M. Lyubchanskaya, L. M. Alekseeva, I. S. Nikolaeva, et al., Khim.-farm. Zh., No. 4, 35–37 (1991).

    Google Scholar 

  89. I. Bador-Lamblung and I. C. Bardin, Electrochim. Acta,19, 725–731 (1974).

    Google Scholar 

  90. R. C. Paul and R. Parkash, Res. Bull. Punjab. Univ.,22, No. 1–11, 193–200 (1971).

    Google Scholar 

  91. V. G. Granik, Usp. Khim.,51, No. 2, 207–239 (1982).

    Google Scholar 

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Authors and Affiliations

  1. Center for Drug Chemistry, All-Union Scientific-Research Institute for Pharmaceutical Chemistry, Moscow

    V. G. Granik, V. M. Lyubchanskaya & T. I. Mukhanova

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  1. V. G. Granik
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  2. V. M. Lyubchanskaya
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Translated from Khimiko-farmatsevticheskii Zhurnal, Vol. 27, No. 6, pp. 37–55, June, 1993.

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Granik, V.G., Lyubchanskaya, V.M. & Mukhanova, T.I. The Nenitzescu reaction (review). Pharm Chem J 27, 413–438 (1993). https://doi.org/10.1007/BF00780660

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