Pharmaceutical Chemistry Journal

, Volume 27, Issue 11, pp 789–796 | Cite as

A study of human recombinant insulin S-sulfonation conditions

  • L. S. Zhigis
  • E. M. Rapoport
  • V. S. Zueva
  • P. D. Reshetov
Methods of Synthesis and Technology of Drug Manufacture


Organic Chemistry Human Recombinant Insulin Recombinant Insulin 
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  1. 1.
    J. L. Bailey and R. D. Cole, J. Biol. Chem.,234, 1733 (1959).Google Scholar
  2. 2.
    H. F. Bruce, US Patent Appl. No. 349,397, prior 16.02.1982.Google Scholar
  3. 3.
    W. D. Busse and H. G. Gattner, Hoppe-Seyler's Z. Physiol. Chem.,354, 147–155 (1973).Google Scholar
  4. 4.
    W. C. Chan William, J. Biochem.,12, 4247–4254 (1968).Google Scholar
  5. 5.
    R. D. Cole, Methods Enzymol.,11, 206 (1967).Google Scholar
  6. 6.
    G. H. Dixon and A. C. Wardlaw, Nature (London),188, 721 (1960).Google Scholar
  7. 7.
    D. V. Goeddel and D. G. Kleid, Itakura Keiicin Europ. Patent Appl. No. 81306193,4, prior 02.01.81.Google Scholar
  8. 8.
    K. Hejnaes and T. Christensen, in: 1st Conference on Advances in Purification of Recombinant Proteins, Abstracts, Interlaken, Switzerland (1989).Google Scholar
  9. 9.
    P. J. Katsoyannis, A. Tometsko, C. Zalut, et al., J. Biochem.,6, 2635 (1967).Google Scholar
  10. 10.
    K. Kobaschi and B. L. Horecker, Arch. Biochem.,121, 178 (1967).Google Scholar
  11. 11.
    R. G. Righetti and J. W. Drysdale, J. Chromatogr.,98, 271–321 (1974).Google Scholar
  12. 12.
    Th. Ruegg Urs and H. G. Gattner, Hope-Seyler's Z. Physiol. Chem.,356, 1527–1537 (1975).Google Scholar
  13. 13.
    J. M. Swann, Nature,180, 643–645 (1957).Google Scholar

Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • L. S. Zhigis
    • 1
  • E. M. Rapoport
    • 1
  • V. S. Zueva
    • 1
  • P. D. Reshetov
    • 1
  1. 1.M. M. Shemyakin Institute of Bioorganic ChemistryRussian Academy of SciencesMoscow

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