Vaccinal tularemic infection in guinea pigs affected by radiation sickness

  • A. S. Shevelev
Pathological Physiology and General Pathology


Different doses of x-rays (from sublethal to 50–70 LD)administered 24 hours before the vaccination or 24 hours after it do not cause exacerbation of the vaccinal tularemic infection in guinea pigs immunized with live microbes of vaccinalB. tularense strain. As shown, no reversion of the vaccinalB. tularense strain is possible in these conditions. In our experiments irradiation had a more pronounced effect on the allergic reconstruction of the body than on the formation of the antibodies, and this is probably due to a more pronounced radiosensitivity of the mechanisms effecting the process of allergization of the body as compared to those of antibody formation.


Public Health Pronounced Effect Antibody Formation Experiment Irradiation Radiation Sickness 
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Literature Cited

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    G.A. Chekatilo, Sectional Papers Presented to the All-Union Conference on Medical Radiology. Section of Experimental Radiology, p. 103, Moscow, 1956 [in Russian].Google Scholar
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    G.A. Chekatilo, Med. Radiol., No. 2, 37–42 (1958).Google Scholar
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    A.S. Shevelev, Proceedings of the 11th Scientific Conference of the Smolensk State Medical Institute, pp. 148–149, Smolensk, 1957 [in Russian].Google Scholar
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    A.S. Shevelev, Med. Radiol., No. 4, pp. 50–56 (1958).Google Scholar

Copyright information

© Consultants Bureau, Inc. 1959

Authors and Affiliations

  • A. S. Shevelev
    • 1
    • 2
  1. 1.Department of Microbiology of the Smolensk Medical InstituteSmolenskUSSR
  2. 2.Department of Roentgenology and Radiology of the Smolensk Medical InstituteSmolenskUSSR

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