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Mitogenetic analysis of the protein framework of protoplasm communication III. Special features of the framework of the cancer cell

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

By the method of mitogenetic spectral analysis it has been demonstrated that the protein substrate of cancer cells differs from the substrate of the normal tissue in which cellular division occurs. In 21–24 second exposures amino- and hydroxyl end groups have been revealed in the cancer tissue. Irradiations characterizing these radicals are found in 10–12-second exposures of the tissues of newborn guinea pigs containing dividing cells. At the same time the mitogenetic spectri of the cancer tissue characterizing the carboxyl (R−C−O) and the oxyphenyl (R−C6−H4OH) groups are widened in comparison with the bands peculiar to the normal tissues with dividing cells. Hence it may be assumed that the cancer cell substrate consists of short (with relation to the main axis) two and “three-dimentional agreggates”. Administration of the mitogenetic radiation extinguisher (fufurol solution) to mice has demonstrated the short chains to be related to the constancy of the radiation specific for cancer cells.

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Literature Cited

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  2. A. G. Gurvich and L. D. Gurvich, Introduction to the Study of Mitogenesis. (Moscow, 1948). [In Russian].

  3. A. G. Gurvich, L. D. Gurvich, S. Ya. Zalkind et al., A Cancer Extinguisher. (Moscow, 1947). [In Russian].

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Slavina, N.S. Mitogenetic analysis of the protein framework of protoplasm communication III. Special features of the framework of the cancer cell. Bull Exp Biol Med 47, 463–467 (1959). https://doi.org/10.1007/BF00779627

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  • DOI: https://doi.org/10.1007/BF00779627

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