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Effect of glutamic acid on cholinergic excitation in central and peripheral synapses

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

It has been established experimentally that glutamic acid depresses the contractile activity of frog rectus abdominis muscle under the influence of neostigmine methylsulfate, and reduces the percentage of white mice suffering convulsions or death after neostigmine methylsulfate poisoning. The author suggests that these effects of glutamic acid may be explained by its action upon the synthesis or binding of acetycholine.

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Authors and Affiliations

  1. Department of Pharmacology of the Leningrad Pediatric Medical Institute, Leningrad, USSR

    P. E. Dyablova

Authors
  1. P. E. Dyablova
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Dyablova, P.E. Effect of glutamic acid on cholinergic excitation in central and peripheral synapses. Bull Exp Biol Med 49, 68–70 (1960). https://doi.org/10.1007/BF00779580

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  • DOI: https://doi.org/10.1007/BF00779580

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