Summary
The number of mitoses was studied in the epithelium of Lieberkühn's crypts in control and hypophysectomized rats sacrificed at different times of the day. Hypophysectomy provoked no changes of the mitotic activity (as estimated per 1000 cells) nor of the diurnal rhythm of cell division. However, the number of cells in the crypts of the small intestine proved to be diminished in hypophysectomized animals.
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Literature Cited
Vorontsova, M. A., Regeneration of Lost Organs in Animals and Man [in Russian] (Moscow, 1953).
Gasanov, S. G., Probl. endokrinol. i gormonoter.5, 5, 40 (1959).
Gluzman, F. A., Vrach. Delo, No. 2, p. 165 (1959).
Gololobova, M. T., Byull. Éksptl. Biol. i Med., No. 9, p. 118 (1958).
Kabak, Ya. M. Studies in the Dynamics of Development [in Russian] (Moscow, 1931) Vol. 6, p. 11.
Kandel', E. I., Voprosy Neirokhir., No. 5, p. 56, (1959).
Astarabadi, T. M., Essex, H. E. and Grindlay, J. H., Endocrinology52, 652 (1953).
Blumenfeld, C. M., Arch. Path.35, 667 (1943).
Braun-Menendez, E. and Houssay, H. E. J., C. R. Soc. Biol.143, 1255 (1949).
Brolin, S. E. and Hellman, B., Acta path. microbiol. scand.38, 433 (1956).
Bullough, W. S., Proc. Roy. Soc. B.135, 879 212 (1948).
Haeger, K., Jacobsohn, D. and Kahlson, G., Acta physiol. scand.30, 111, p. 161 (1953).
Klein, H. and Geisel, H., Klin. Wschr.24–25, 626 (1947).
Leblond, C. P. and Carriere, R., Endocrinology56, 261 (1955).
Luft, R. and Olivecrona, H., Neurosurgery10, 301 (1953).
Rolt, D. and White, H. L., Endocrinology53, 436 (1953).
Teir, H. and Carpén, I., Acta path. microbiol. scand.47, 291 (1959).
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Raitsina, S.S. Physiological regeneration in the mucosa of the small intestine of hypophysectomized rats. Bull Exp Biol Med 51, 494–497 (1961). https://doi.org/10.1007/BF00779542
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DOI: https://doi.org/10.1007/BF00779542