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Effect of antisera specific for irradiated malignant tissues on the growth of experimental tumors in animals subjected to irradiation

Communication I. Capacity of irradiated antigens to provoke the formation of antibodies in animals of various species

  • Microbiology and Immunology
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Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The work was devoted to the study of the effect of penetrating radiation, particularly of x-rays, on the ability of the cells of mice Ehrich's cancer, rabbit Brown-Pearce carcinoma and human cancer of the stomach to produce antibody formation in various species of animals. The data obtained point to the fact that x-rays acting in vitro upon the cells of these tumors change their immunological properties. This is manifested in a reduced ability of antisera (obtained by immunization of animals with irradiated tumor cells) to interact with analogous antigens.

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Literature Cited

  1. Blokhina, V. D., Med. Radiol.4, 1, 53 (1959).

    Google Scholar 

  2. Gintsburg, M. B., Biokhimiya, No. 6, p. 840 (1958).

    Google Scholar 

  3. Kiselev, P. N., Sivertseva, V. N. and Karpova, E. V., Zhurn. Mikrobiol., Épidemiol. i Immunobiol., No. 10, p. 21 (1958).

    Google Scholar 

  4. Klemparskaya, N. N., Med. Radiol.3, 3, 85 (1958).

    Google Scholar 

  5. Klemparskaya, N. N., Zhurn. Mikrobiol., Épidemiol. i Immunobiol., No. 11, p. 72 (1959).

    Google Scholar 

  6. Klemparskaya, N. N. et. al., Question of Infection, Immunity, and Allergy in Acute Radiation Sickness [in Russian] (Moscow, 1958).

  7. Libinzon, R. E., Biofizika 4, 1, 89 (1959).

    Google Scholar 

  8. Maiskii, I. N. and Suvorova, G. V., Byull. Éksper. Biol. i Med., No. 9, No. 94 (1957).

  9. Maiskii, I. N. and Suvorova, G. V., in: Problems in the Transplantation and Conservation of Organs and Tissues [in Russian] (Moscow, 1959) p. 98.

  10. Maiskii, I. N., G. V. Suvorova and P. P. Filatov, Byull. Éksper. Biol. i Med., No. 7, p. 72 (1959).

    Google Scholar 

  11. Petrov, R. V. and Il'ina, L. I., Byull. Éksper. Biol. i Med., No. 4, p. 59 (1956).

    Google Scholar 

  12. Prokopenko, L. G., Zhurn. Mikrobiol., Épidemiol. i Immunobiol., No. 9, p. 122 (1959).

    Google Scholar 

  13. Troitskii, V. L. and Tumanyan, M. A., The Effect of Ionizing Radiation on Immunity [in Russian] (Moscow, 1958).

  14. Troitskii, V. L., M. A. Tumanyan and A. Ya. Fridenshtein, Zhurn. Mikrobiol., Épidemiol. i Immunobiol., No. 6, p. 3 (1958).

    Google Scholar 

  15. Bettendorf, G. and Maass, H., Strahlentherapie106, 263 (1958).

    Google Scholar 

  16. Hartiala, K., Näntö, V. and Rinn, U. K., Acta physiol. scand.45, 231 (1959).

    Google Scholar 

  17. Mefferd, R. B., Webster, W. W. and Nyman, M. A., Radiat. Res.8, 461 (1958).

    Google Scholar 

  18. Pany, J., Strahlentherapie108, 531 (1959).

    Google Scholar 

  19. Salermo, P. R. and Friedell, H. L., Radiat. Res.9, 478 (1958).

    Google Scholar 

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Authors and Affiliations

  1. Laboratory of Non-Infectious Immunology of the Institute of Experimental Biology of the Akad. Med. Nauk SSSR, Moscow

    I. N. Maiskii, P. P. Filatov & G. V. Suvorova

Authors
  1. I. N. Maiskii
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  2. P. P. Filatov
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  3. G. V. Suvorova
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Maiskii, I.N., Filatov, P.P. & Suvorova, G.V. Effect of antisera specific for irradiated malignant tissues on the growth of experimental tumors in animals subjected to irradiation. Bull Exp Biol Med 51, 475–478 (1961). https://doi.org/10.1007/BF00779537

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  • DOI: https://doi.org/10.1007/BF00779537

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