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The effect of aimaline on auricular and ventricular arrhythmia in dogs

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The anti-arrhythmic action of aimaline was studied on two models of arrhythmia in dogs. Auricular tibrillation was provoked by mechanical injury and subsequent stimulation of the auricles with induced current; ventricular arrhythmia was caused by ligating the descending branch of the left coronary artery. It was established that aimaline arrests auricular arrhythmia and either sharply reduces the frequency of ventricular extrasystoles or completely eliminates them and decelerates the cardiac activity.

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Authors and Affiliations

  1. Laboratory of Pharmacology and Microbiology of the Khar'kov Institute for Scientific Research in Pharmaceutical Chemistry, Khar'kov, USSR

    E. I. Gendenshtein

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  1. E. I. Gendenshtein
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Gendenshtein, E.I. The effect of aimaline on auricular and ventricular arrhythmia in dogs. Bull Exp Biol Med 51, 456–460 (1961). https://doi.org/10.1007/BF00779533

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  • DOI: https://doi.org/10.1007/BF00779533

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