Summary
The present study demonstrates that protein biosynthesis can be studied in single isolated human scalp hair follicles. The matrix and the sheath are the main regions where amino acids are built in. Incorporation is linear for at least five hours. The newly synthesized proteins can be separated into a water-soluble, a urea-soluble and a urea-insoluble fraction. Product analysis has been performed on the first two fractions, revealing different protein patterns.
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Vermorken, A.J.M., Weterings, P.J.J.M. & Bloemendal, H. Protein biosynthesis in isolated human scalp hair follicles. Mol Biol Rep 4, 211–216 (1979). https://doi.org/10.1007/BF00777556
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DOI: https://doi.org/10.1007/BF00777556