Abstract
Information has been collected to stimulate interest regarding the nature and the possible role of mRNP protein phosphorylation in a cytoplasmic control mechanism for protein synthesis. It does not imply a direct relationship between mRNP protein and initiation factors. These proteins have some properties in common (e.g. molecular weight, phosphorylation, protein kinase, mRNA binding activity). We emphasize that some free mRNP may be translatable after modification of their protein by interference factors belonging to other cellular compartments. Thus, some mRNP proteins might possess initiation factor or protein synthetic activity if we accept Spirin's theory, i.e., “Eukaryotic messenger RNA and informosomes omnia mea mecum porto”
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Spirin, A.S., Eur. J. Biochem. 10, 20–35 (1969).
Van Venrooij W.J., Janssen Dick B., Mol. Biol. Rep. 4, 1: 3–8 (1978).
Preobrazhensky A.A., Spirin A.S., Progress in Nucleic Acid Research and Molecular Biology 21, 2–38 (1978).
Egly J.M., Stevenin J., Path. Biol. 25, no 10, 741–754 (1977).
Perry R.P., Kelley D.E., J. Mol. Biol. 35, 37–59 (1968).
Spohr G., Granboulan N., Morel C., Scherrer K., Eur. J. Biochem. 17, 296–318 (1970).
Sugano H., Suda S., Kawada T., Sugano I., Biochim. Biophys. Acta 238, 139–149 (1971).
Gander E.S., Stewart A.G., Morel C., Scherrer K., Eur. J. Biochem. 38, 443–452 (1973).
Soeiro R., Vaughan M.H., Warner J.R., Darnell J.E., J. Cell Biol. 39, 112–118 (1968).
Brandhort B., McConkey E., J. Mol. Biol. 85, 451–463 (1974).
Buckingham M.E., Caput D., Cohen A., Whalen R.G., Gros F., Proc. Nat. Acad. Sci. US 71, 1466–1470 (1974).
Iatrou K., Dixon G.H., Cell 10, 433–441 (1977).
Gross K.W., Jacobs-Lorena M., Baglioni C., Gross P.R., Proc. Nat. Acad. Sci. US 70, 9, 2614–2618 (1973).
Zahringer J., Baliga B.S., Munro H.N., Proc. Nat. Acad. Sci. 73, 857–881 (1976).
Houdebine L.M., Delouis C., Devinoy E., Biochimie 60, 809–812 (1978).
Enger M.D., Campbell E.W., Hanners J.L., Febs. Lett. 55, 194–197 (1975).
Mac Leod C., Biochemistry 14, 4011–4018 (1975).
Freienstein C., Blobel G., Proc. Nat. Acad. Sci. US 71, 3435–3439 (1974).
Ernst V., Arnstein H.R.V., Biochim. Biophys. Acta 378, 251–259 (1975).
Chen J.H., Lavers G.C., Spector A., Biochim. Biophys. Acta 418, 39–51 (1976).
Spohr G., Kayibanda B., Scherrer K., Eur. J. Biochem. 31, 194–208 (1972).
Bag J., Sarkar S., Biochemistry 14, 3800–3807 (1975).
Bag J., Sarkar S., J. Biol. Chem. 251, 7600–7609 (1976).
Civelli O., Vincent A., Buri J.F., Scherrer K., Febs. Lett. 72, 71–76 (1976).
Shafritz D.A., J. Biol. Chem. 249, 81–88 (1974).
Huang A.S., Baltimore D., J. Mol. Biol. 47, 275–291 (1970).
Olsnes S., Eur. J. Biochem. 18, 242–249 (1971).
Kempf J., Egly J.M., Stricker Ch., Schmitt M., Mandel P., Febs. Lett. 26, 1 130–134 (1972).
Lindberg U., Sundquist B., J. Mol. Biol. 86, 451–468 (1974).
Gander E.S., Mueller R.U., Goldenberg S., Morel C., Mol. Biol. Rep. 2, 343–346 (1975).
Liautard J.P., Setyono B., Spindler E., Köhler K., Biochim. Biophys. Acta 425, 373–383 (1976).
Van der Marel, Tasseron de Jong J. G., Bosch L., Febs. Lett. 51, 330–334 (1975).
Auerbach S., Pederson Th. Biochem. Biophys. Res. Commun. 63, 149–156 (1975).
Hellermann J.G., Shafritz D.A., Proc. Nat. Acad. Sci. US 72, 3, 1021–1025 (1975).
Barrieux A., Ingraham H.A., David D.N., Rosenfeld M.G., Biochemistry 14, 1815–1821 (1975).
Mizushima S., Nomura M., Nature 226, 1214–1219 (1970).
Zawislak R., Stevenin J., Jacob M., Biochimie 56, 91–98 (1974).
Egly J.M., Krieger O., Mandel P., Kempf J., Febs. Lett. 40, 101–105 (1974).
Globel G., Proc. Nat. Acad. Sci. US 70, 924–928 (1973).
Gander E.S., Stewart A.G., Morel C., Scherrer K., Eur. J. Biochem. 38, 443–452 (1973).
Egly J.M., Johnson B.C., Stricker Ch. Mandel P., Kempf J., Febs. Lett. 22 181–184 (1972).
Schmitt M., Egly J.M., Mandel P., Kempf J., Biochimie 55, 653–659 (1973).
Quirin-Stricker Ch., Schmitt M., Egly J.M., Kempf J., Eur. J. Biochem. 62, 199–209 (1978).
Quirin-Stricker Ch., Schmitt M., personal communication.
Egly J.M., Elkaim R., Kempf J., submitted for publication.
Liautard J.P., Personal communication.
Schmitt M., Kempf J., Quirin-Stricker Ch., Biochim. Biophys. Acta 481, 438–449 (1977).
Cenatiempo Y., Genot A., Cozzone A.J., Reboud J.P., Biochimie 60, 813–816 (1978).
Fan H., Penman S., J. Mol. Biol. 50, 655–670 (1970).
Pain V.M., Clemens M.J., Febs. Lett. 32, 205–212 (1973).
Palmiter R.D., Cell 4, 189–197 (1975).
Weissbach H., Ochoa L., Ann. Rev. Biochem. 45, 191–216 (1976).
Revel M., Molecular Mechanisms of Protein Biosynthesis 245–321 (1977) Acad. P.N.
Benne R., Hershey J.W.B., Proc. Nat. Acad. Sci. US 73, 3005–3009 (1976).
Benne R., Wong C., Luedi M., Hershey J.W.B., J. Biol. Chem. 251, 7675–7681 (1976).
Benne R., Luedi M.L., Hershey J.W.B. J. Biol. Chem. 252, 5798–5803 (1977).
Benne R., Brown Luedi M.L., Hershey J.W.B., J. Biol. Chem. 253, 3070–3077 (1978)
Schreier M.H., Erni B., Staehelin T., J. Mol. Biol. 116, 727–753 (1977).
Staehelin T., Trachsel H., Erni B., Boschetti A., Schreier M.H., Febs. Proc. Meet 10, 309–323 (1975).
Safer B., Anderson W.F., Merrick W.C., J. Biol. Chem. 250, 9067–9075 (1975).
Merrick W.C., Kemper W.M., Anderson W.F., Proc. Nat. Acad. Sci. US 72, 5556–5562 (1975).
Prichard P.M., Anderson W.F., Methods Enzymol. 30, 136–141 (1974).
Safer B., Adams S.L., Kemper W.M., Berry K.W., Lloyd M., Merrick W.C., Proc. Nat. Acad. Sci. US 73, 2584–2588 (1976).
Kemper W.M., Berry K.W., Merrick W.C., J. Biol. Chem. 251, 5551–5557 (1976).
Benne R., Edman J., Traut R.R., Hershey J.W.B., Proc. Nat. Acad. Sci. US 75, 108–112 (1978).
Traugh J.A., Tahara S.M., Sharp S.B., Safer B., Merrick W.C., Nature 263, 163–165 (1976).
Issinger O.G., Benne R., Hershey J.W.B., Trau R.R., J. Biol. Chem. 251, 6471–6474 (1976).
Levin D.H., Ranu R.S., Ernst V., London I.M., Proc. Nat. Acad. Sci. US 73, 3112–3116 (1976).
Kramer G., Cimadevilla M.J. Hardesty B., Proc. Nat. Acad. Sci. US 73, 3078–3082 (1978).
Farrell P.J., Balkow K., Hunt T., Jackson R.J., Cell 11, 187–200 (1977).
Ranu R.S., London I.M., Das A., Dasgupta A., Majumdar A., Ralston R., Roy R., Gupta N.K., Proc. Nat. Acad. Sci. US 75, 745–749 (1978).
Maxwell C.R., Kamper C.S., Rabinovitz M., J. Mol. Biol. 58, 317–327 (1971).
Farrell P.J., Hunt T., Jackson R.J., Eur. J. Biochem. 89, 517–521 (1978).
Datta A., De Haro C., Sierra J.M., Ochoa L., Proc. Nat. Acad. Sci. US 74, 1463–1467 (1977).
Pierre M., Loeb J.E., Biochem. Biophys. Res. Commun. 77, 481–488 (1977).
Zilberstein A., Federman P., Shulman L., Revel M., Febs Lett. 68, 119–124 (1976).
Lebleu B., Sen G.C., Shaila S., Cabrer B., Lengyel P., Proc. Nat. Acad. Sci. US 73, 3107–3111 (1976).
Roberts W.K., Hovanessian A., Brown R.E., Clemens M.J., Kerr I.M., Nature 264, 477–480 (1976).
Pinphanichakarn P., Kramer G., Hardesty B., J. Biol. Chem. 252, 2106–2112 (1977).
Benne R., Hershey J.W.B., J. Biol. Chem. 253, 3078–3087 (1978).
Golini F., Thach S.S., Birge C.H., Safer B., Merrick W.C., Thach R.E., Proc. Nat. Acad. Sci. US 73, 3040–3044 (1976).
Kabat D., Chappel M.R., J. Biol. Chem. 252, 2684–2690 (1977).
Shafritz D.A., Weinstein J.A., Safer B., Merrick W.C., Weber L.A., Hickey E.D., Baglioni C., Nature 261, 291–294 (1976).
Merrick W.C., Peterson D.T., Safer B., Lloyd M., Kemper W.M., Febs Meeting Gene Expression, Clark Br., Klenow M. Eds, Pergamon Press Vol. 43, 17–27 (1977).
Pahlmann S., Rosengren J., Hjerten S., J. Chromatogr. 131, 99–108 (1977).
Shafritz D.A., Molecular Mechanisms of Protein Biosynthesis (Weisbach M. Pelska S. Eds, Academic Press (1977)).
Lingrel J.B., Lockard R.E., Jones R.F., Burr H.E., Holder J.W., Ser Haematal 4, 3–10 (1971).
Sampson J., Mathews M.B., Osborn M., Borghetti A.F., Biochemistry 11, 3636–3640 (1972).
Hendrick D., Schwarz W., Pitzel S., Tiedemann H. Biochim. Biophys. Acta 340 278–284 (1974).
Cashion L.M., Stanley W.M. Jr., Proc. Nat. Acad. Sci US 71, 436–440 (1974).
Barrieux A., Rosenfeld M.A., J. Biol. Chem. 252, 392–398 (1977).
Jergil B., Eur. J. Biochem. 28, 546–554 (1972).
Tao M., Salas M.T., Lipman F., Proc. Nat. Acad. Sci. US 67, 408–414 (1970).
Egly J.M., Schmitt M., Kempf J., Biochim. Biophys. Acta 454, 549–557 (1976).
Quirin Stricker Ch., Schmitt M., Biochim. Biophys. Acta 477, 414–426 (1977).
Rubin Ch.S., Rosen O.M., Annu. Rev. Biochem. 831–887 (1975).
Ovchinnikov L.P., Spirin A.S., Erni B., Stachelin T., Febs Lett. 88, 21–26 (1978).
Miller R.L., Schweet R., Arch. Biochem. Biophys. 125, 632–646 (1968).
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Egly, J.M., Elkaim, R. & Pierre, M. mRNP proteins, initiation factors and phosphorylation. Mol Biol Rep 5, 91–97 (1979). https://doi.org/10.1007/BF00777494
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DOI: https://doi.org/10.1007/BF00777494