Molecular Biology Reports

, Volume 6, Issue 1, pp 35–38 | Cite as

Detection of an enzyme activity which cleaves m7 Guanine from m7 GMP in an extract of embryonic chick lens cells

  • Gregory Gang
  • Gene C. Lavers


m7 Guanine was cleaved from m7 GMP by cytoplasmic enzyme activity in an extract prepared from embryonic chick lens cells. The appearance of m7-Guanine was proportional tot he time and concentration of extract. m7-Guanine inhibited the reaction but neither guanine nor ribose 5-phosphate did. m7 Guanine may be derived from m7 GpppG mRNA cap by two enzymatic reactions with m7 GMP as a product-substrate intermediate.


Enzyme Activity Guanine Enzymatic Reaction Ribose Embryonic Chick 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Lavers, G.C., Exp. Eye Res. 28, 299–309 (1979).Google Scholar
  2. 2.
    Lavers, G.C., Mol. Biol. Reports 3, 275–281 (1979).Google Scholar
  3. 3.
    Lavers, G.C., Mol. Biol. Reports 3, 413–420 (1977).Google Scholar
  4. 4.
    Lavers, G.C., Mol. Biol. Reports 4, 233–236 (1978).Google Scholar
  5. 5.
    Hendler, S., Fürer, E. and Srinivasan, P.R., Biochemistry 9, 4141–4153 (1970).Google Scholar
  6. 6.
    Shapiro, R., Prog. Nuc. Acid Res. and Mol. Biol. 1, 73–112 (1968).Google Scholar
  7. 7.
    Hall, R.H., The Modified Nucleosides in Nucleic Acids. Columbia University Press, New York, 1971.Google Scholar

Copyright information

© Dr. W. Junk B.V. Publishers, The Hague 1980

Authors and Affiliations

  • Gregory Gang
    • 1
  • Gene C. Lavers
    • 1
  1. 1.Department of BiochemistryNew York University Dental CenterNew YorkUSA

Personalised recommendations