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Selective muscarinic ligands (a review)

  • Molecular Biological Problems of the Creation of Drugs and Study of the Mechanism of their Action
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Pharmaceutical Chemistry Journal Aims and scope

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Literature cited

  1. V. M. Arutyunyan and G. A. Minosyan, Sov. Meditsina, No. 7, 45–48 (1989).

    Google Scholar 

  2. V. B. Dolgo-Saburov, Farmakol. Toksikol.,52, 100–105 (1989).

    Google Scholar 

  3. V. B. Dolgo-Saburov and Yu. A. Shorokhov, Molecular Mechanisms of the Functioning of Muscarinic Cholinergic Receptors. Results of Science and Technology. Pharmacology. Chemotherapeutic Agents [in Russian], Vol. 19, Moscow (1989), pp. 20–81.

    Google Scholar 

  4. É. V. Zeimal' and S. A. Shelkovnikov, Muscarinic Cholinoreceptors [in Russian], Leningrad (1989).

  5. Yu. R. Mirzaev, Sixth All-Union Conference of Pharmacologists. Summaries of Reports [in Russian], Tashkent (1988), p. 250.

  6. Yu. R. Mirzaev, Dokl. Akad. Nauk Uzbek SSR, No. 6, 48–50 (1988).

    Google Scholar 

  7. E. S. Ryss and Yu. I. Fishzon-Ryss, Sov. Meditsina, No. 11, 37–41 (1989).

    Google Scholar 

  8. S. Yu. Yunusov, Alkaloids [in Russian], Tashkent (1981), p. 42.

  9. Khim.-farm. Promyshlennost' za Rubezhom, No. 9, 18 (1990).

  10. M. De Amici, E. De Micheli, and E. Grana, Eur. J. Med. Chem.,24, 171–177 (1989).

    Google Scholar 

  11. S. Amstutz, B. Ringdahl, B. Karlen, et al., J. Med. Chem.,28, 1760–1765 (1985).

    Google Scholar 

  12. P. Angeli, L. Brasili, F. Gualtieri, et al., Naunyn-Schmiedeberg's Arch. Pharmacol.,337, 241–245 (1988).

    Google Scholar 

  13. R. B. Barlow, K. N. Burston, and A. Vis, Br. J. Pharmacol.,68, 141–142 (1980).

    Google Scholar 

  14. R. B. Barlow, M. K. Shepherd, H. Tydeman, and M. A. Veale, ——ibid.,94, 947–950 (1988).

    Google Scholar 

  15. R. B. Barlow and O. Johnson, ——ibid.,98, 425–429 (1989).

    Google Scholar 

  16. R. B. Barlow, D. W. Holdup, G. Harris, et al., ——ibid.,99, 622–626 (1990).

    Google Scholar 

  17. D. Batink, D. Davidesco, H. N. Doods, et al., ——ibid.,90, Proceed. Suppl., 81 (1987).

    Google Scholar 

  18. J. Baumgold and A. Drobnick, Mol. Pharmacol.,36, 465–470 (1989).

    Google Scholar 

  19. G. Berstein, T. Haga, and A. Ichiyama, ——ibid.,36, 601–607 (1989).

    Google Scholar 

  20. N. J. M. Birdsall, C. A. M. Curtis, Pharmacology,37, Suppl. 1, 22–31 (1988).

    Google Scholar 

  21. T. I. Bonner, Trends Neurosci.,12, 148–151 (1989).

    Google Scholar 

  22. B. J. Bradbury, J. Baumgold, and K. A. Jacobson, J. Med. Chem.,33, 741–748 (1990).

    Google Scholar 

  23. M. P. Caufield, J. K. Stabley, Br. J. Pharmacol.,76, Suppl. 216 (1982).

  24. K. J. Van Charldorp, J. Davidesco, and P. A. Van Zwieten, Eur. J. Pharmacol.,150, 197–199 (1988).

    Google Scholar 

  25. K. J. Van Chardorp, H. D. Batink, and F. Mol, Naunyn-Schmiedeberg's Arch. Pharmacol.,339, Supp., 328 (1989).

    Google Scholar 

  26. R. U. Clague, R. M. Eglen, A. C. Strahan, and R. L. Whiting, Br. J. Pharmacol.,86, 163–170 (1985).

    Google Scholar 

  27. V. I. Conen, J. Pharmacol. Sci.,76, 848–850 (1987).

    Google Scholar 

  28. E. Giacobini and R. Becker (eds.), Current Research in Alzheimer Therapy: Cholinesterase Inhibitors, New York (1988).

  29. E. Decorte, G. Gratton, T. Kovac, et al., Farmaco Ed. Sci.,37, 787–796 (1982).

    Google Scholar 

  30. F. De Ponti, L. Ambrosoli, M. Borsa, and L. Dangelo, Pharmacology,38, 374–380 (1989).

    Google Scholar 

  31. H. N. Doods, M. J. Mathy, D. Davidesco, et al., J. Pharmacol. Exp. Ther.,242, 257–262 (1987).

    Google Scholar 

  32. H. N. Doods and N. Mayer, Eur. J. Pharmacol.,161, 215–218 (1989).

    Google Scholar 

  33. H. N. Doods, Naunyn-Schmiedeberg's Arch. Pharmacol.,339, Suppl., 327 (1989).

    Google Scholar 

  34. W. G. Eberlein, G. Trummlitz, W. W. Engel, et al., J. Med. Chem.,30, 1378–1381 (1987).

    Google Scholar 

  35. W. G. Eberlein, W. W. Engel, G. Trummlitz, and G. Schmidt, ——ibid.,31, 1169–1174 (1988).

    Google Scholar 

  36. W. G. Eberlein, W. W. Engel, G. Trummlitz, et al., Trends Pharmacol. Sci.,9, Suppl., 79 (1988).

    Google Scholar 

  37. W. C. Eckelman, M. Grissom, J. Conklin, et al., J. Pharmacol. Sci.,73, 529–534 (1984).

    Google Scholar 

  38. R. M. Eglen, W. W. Montgomery, C. A. Machado, and R. R. Whiting, Br. J. Pharmacol.,98, Suppl., 662 (1989).

    Google Scholar 

  39. M. Eltze, S. Gonne, R. Riedel, et al., Eur. J. Pharmacol.,112, 211–224 (1985).

    Google Scholar 

  40. M. Eltze, G. Grundler, and C. Schudt, Naunyn-Schmiedeberg's Arch. Pharmacol.,338, Suppl., 194 (1988).

    Google Scholar 

  41. M. Eltze and V. Figava, Eur. J. Pharmacol.,158, 11–19 (1988).

    Google Scholar 

  42. W. W. Engel, W. G. Eberlein, G. Mihm, and R. Hammer, J. Med. Chem.,32, 1718–1724 (1989).

    Google Scholar 

  43. P. Evileigh, E. C. Hulme, C. Schudt, and N. J. Birdsall, Mol. Pharmacol.,35, 477–484 (1989).

    Google Scholar 

  44. R. Feifel, A. Assen, C. Strohmann, and R. Tacke, Naunyn-Schmiedeberg's Arch. Pharmacol.,338, Suppl., 193 (1988).

    Google Scholar 

  45. R. Feifel, M. Wagner-Roder, and C. Strohmann, Br. J. Pharmacol.,99, 455–560 (1990).

    Google Scholar 

  46. B. V. Franco, J. W. Ward, and R. S. Alphin, J. Pharmacol. Exp. Ther.,139, 25–30 (1963).

    Google Scholar 

  47. S. B. Freedman, M. S. Beer, E. A. Harlay, Eur. J. Pharmacol.,156, 133–143 (1988).

    Google Scholar 

  48. J. Gaal, J. Batke, A. Borsodi, and L. Rozsa, Acta Biochem. Biophys. Hung.,24, 129–142 (1989).

    Google Scholar 

  49. A. Giachetti, U. Muttmann, J. H. Brown, et al., Fed. Proceed.,46, 2523–2535 (1987).

    Google Scholar 

  50. R. E. Gibson, W. J. Rzeszotarski, W. C. Eckelman, et al., Biochem. Pharmacol.,32, 1851–1856 (1983).

    Google Scholar 

  51. R. E. Gibson, W. J. Rzeszotarski, E. M. Jagoda, et al., Life Sci.,34, 2287–2296 (1984).

    Google Scholar 

  52. S. A. H. Gilani, L. B. Cobbin, Trends Pharmacol. Sci.,9, Suppl., 87–88 (1988).

    Google Scholar 

  53. E. Giraldo, R. Micheletti, E. Montagna, and A. Giachetti, J. Pharmacol. Exp. Ther.1,244, 1016–1021 (1988).

    Google Scholar 

  54. R. K. Coyal, N. Engl. J. Med.,321, 1022–1029 (1989).

    Google Scholar 

  55. F. J. Grews, E. M. Meyer, and R. A. Gonzales, Treat. Dev. Strateg. Alzheimer's Disease, Madison, Conn. (1986), pp. 385–419.

  56. T. Haga, G. Berstein, T. Nishiyama, et al., Neuroreceptors and Signal Transduction, S. Kito et al (ed.), New York (1988), pp. 239–254.

  57. A. J. Hunter, T. K. Murrau, J. A. Jones, et al., Br. J. Pharmacol.,98, 79–86 (1989).

    Google Scholar 

  58. B. J. Jackson, L. Strum, and L. Noronha-Blob, FASEB Journal,3, No. 3, Part 1, 3850 (1989).

    Google Scholar 

  59. A. Kalman, L. Parkanyi, and K. Valko, Acta Biochem. Biophys. Hung.,24, 143–158 (1989).

    Google Scholar 

  60. A. R. Kerlavage, C. M. Fraser, and V. J. Craig, Trends Pharmacol. Sci.,8, 426–431 (1987).

    Google Scholar 

  61. P. Krogsgaard-Larsen, E. Falch, P. Sauerberg, et al., ——ibid.,9, Suppl., 69–74 (1988).

    Google Scholar 

  62. A. Lagersted and F. S. Jorgensen, Progress in Clinical and Biological Research, Vol. 29k, New York (1989), pp. 333–336.

    Google Scholar 

  63. G. Lambrecht, R. Feifel, U. Moser, et al., Eur. J. Pharmacol.,155, 167–171 (1988).

    Google Scholar 

  64. G. Lambrecht, R. Feifel, B. Forth, and C. Strohmann, Maunyn-Schmeideberg's Arch. Pharmacol.,338, Supp., 186 (1988).

    Google Scholar 

  65. G. Lambrecht, R. Feifel, B. Forth, and C. Strohmann, Eur. J. Pharmacol.,152, 193–194 (1988).

    Google Scholar 

  66. G. Lambrecht, R. Feifel, and M. Wagner-Roder, ——ibid.,168, 71–80 (1989).

    Google Scholar 

  67. G. Lambrecht, R. Feifel, C. Strohmann, et al., Naunyn-Schmiedeberg's Arch. Pharmacol.,339, Suppl., 324 (1989).

    Google Scholar 

  68. G. Lambrecht, G. Gmelin, and U. Moser, ——ibid.,337, Suppl., 336 (1988).

    Google Scholar 

  69. G. Lambrecht, G. Gmelin, K. Rafeiner, and C. Strohmann, Eur. J. Pharmacol.,151, 155–156 (1988).

    Google Scholar 

  70. G. Lambrecht, E. Mutschler, J. Wess, et al., ——ibid.,142, 475–478 (1987).

    Google Scholar 

  71. J. W. J. Lammers, P. Minettle, M. McCuscer, and P. J. Barnes, Am. Rev. Resp. Disease,139, 446–449 (1989).

    Google Scholar 

  72. S. Lasareno and F. Roberts, Br. J. Pharmacol.,95, Supp., 743 (1988).

    Google Scholar 

  73. P. Left, I. G. Dougall, D. J. Harper, and I. A. Daintly, Trends Pharmacol. Sci.,11, 64–67 (1990).

    Google Scholar 

  74. J. R. M. Lundkvist, B. Ringdahl, and U. Hacksell, J. Med. Chem.,32, 863–869 (1989).

    Google Scholar 

  75. N. Mayer, Naunyn-Schmiedeberg's Arch. Pharmacol.,339, Suppl., 326 (1989).

    Google Scholar 

  76. N. Mayer and H. N. Doods, ——ibid.,337, Suppl., 365 (1988).

    Google Scholar 

  77. L. Mei, W. R. Roeske, and H. I. Yamamura, Life Sci.,45, 1831–1851 (1989).

    Google Scholar 

  78. C. Melchiorre, Trends Pharmacol. Sci.,9, 216–220 (1988).

    Google Scholar 

  79. C. Melchiorre, A. Cassinelli, and W. Quaglia, J. Med. Chem.,30, 201–204 (1987).

    Google Scholar 

  80. C. Melchiorre, W. Quaglia, and M. T. Picehio, ——ibid.,32, 79–84 (1989).

    Google Scholar 

  81. C. Mellin, H. M. Vargas, and B. Ringdahl, ——ibid.,32, 79–84 (1989).

    Google Scholar 

  82. A. D. Michel, Eur. J. Pharmacol.,145, 61–66 (1988).

    Google Scholar 

  83. A. D. Michel, E. Stefanich, and R. L. Whiting, ——ibid.,166, 459–467 (1989).

    Google Scholar 

  84. F. Mitchelson, L. K. Choo, S. Dorroch, Clin. Exp. Pharmacol. Physiol.,16, 523–528 (1989).

    Google Scholar 

  85. U. Moser, G. Lambert, M. Wagner, et al., Br. J. Pharmacol.,96, 319–324 (1989).

    Google Scholar 

  86. E. Mutschler, P. Angeli, G. Lambrecht, et al., Trends Pharmacol. Sci.,9, Suppl., 80–81 (1988).

    Google Scholar 

  87. E. Mutschler and G. Lambrecht, ——ibid.,5, Suppl., 39–44 (1984).

    Google Scholar 

  88. E. Mutschler, U. Moser, R. Feifel, and K. Refeiner, Naunyn-Schmiedeberg's Arch. Pharmacol.,338, Suppl., 191 (1988).

    Google Scholar 

  89. E. Mutschler, U. Moser, J. Wess, and G. Lambrecht, Recent Advances in Receptor Chemistry, Amsterdam (1988), pp. 195–198.

  90. N. Nakahara, J. Iga, A. Saito, et al., Jpn. J. Pharmacol.,51, 539–547 (1989); Chem. Abstr.,112, No. 48620k (1990).

    Google Scholar 

  91. B. M. Nilsson, B. Ringdahl, and U. Hacksell, J. Med. Chem.,31, 577–582 (1988).

    Google Scholar 

  92. B. M. Nilsson, B. Ringdahl, and U. Machsell, ——ibid.,33, 580–584 (1990).

    Google Scholar 

  93. L. Nilvebrant and B. Sparf, Trends Pharmacol. Sci.,9, Suppl., 83 (1988).

    Google Scholar 

  94. O. Nordstrom, P. Albert, A. Westlind, et al., Mol. Pharmacol.,24, 1–5 (1983).

    Google Scholar 

  95. S. Ono and J. Saito, Eur. J. Pharmacol.,155, 77–84 (1988).

    Google Scholar 

  96. L. T. Potter and C. A. Ferrendelli, J. Pharmacol. Exp. Ther.,248, 974–979 (1989).

    Google Scholar 

  97. J. Ramachandran, E. G. Peralta, A. Ashkenazi, et al., Computer-Assisted Modeling of Receptor-Ligand Interactions. Theoretical Aspects and Application to Drug Design, New York (1989), pp. 317–340.

    Google Scholar 

  98. B. Ringdahl, ——Cited [100] (1979).

    Google Scholar 

  99. B. Ringdahl, J. Med. Chem.,31, 683–688 (1988).

    Google Scholar 

  100. B. Ringdahl and D. J. Jenden, Mol. Pharmacol.,23, 17–25 (1983).

    Google Scholar 

  101. B. Ringdahl, J. Pharmacol. Exp. Ther.,229, 199–206 (1984).

    Google Scholar 

  102. B. Ringdahl, M. Roch, and D. J. Jenden, ——ibid.,242, 464–472 (1987).

    Google Scholar 

  103. F. Roberts and S. Lasareno, Biochem. Soc. Trans.,17, 76–79 (1989).

    Google Scholar 

  104. M. Romanelli, F. Gualtiery, J. Med. Chem.,31, 1703–1708 (1988).

    Google Scholar 

  105. M. Romanelli, F. Gualtiery, and P. Angeli, ——ibid.,32, 2269–2273 (1989).

    Google Scholar 

  106. M. Romanelli and E. Teodory, ——ibid.,31, 1698–1703 (1988).

    Google Scholar 

  107. A. P. Roszkowski, J. Pharmacol. Exp. Ther.,132, 156–170 (1961).

    Google Scholar 

  108. W. J. Rzeszotarski, R. E. Gibson, and W. C. Eckelman, J. Med. Chem.,25, 1103–1106 (1982).

    Google Scholar 

  109. W. J. Rzeszotarski, W. C. Eskelman, B. E. Francis, et al., ——ibid.,27, 156–159 (1984).

    Google Scholar 

  110. W. J. Rzeszotarski, D. W. McPherson, and J. W. Ferkany, ——ibid.,31, 1463–1466 (1988).

    Google Scholar 

  111. P. Sauerberg, E. Falch, E. Heier, and H. L. Lembol, ——ibid.,31, 1312–1316 (1988).

    Google Scholar 

  112. P. Sauerberg, B. Fjalland, J. J. Larsen, et al., Eur. J. Pharmacol.,130, 125–131 (1986).

    Google Scholar 

  113. J. Saunders, M. Cassidi, S. B. Freedman, et al., J. Med. Chem.,33, 1128–1138 (1990).

    Google Scholar 

  114. J. Saunders, G. A. Showell, Baker, et al., ——ibid.,30, 969–975 (1987).

    Google Scholar 

  115. J. Saunders and G. A. Showell, ——ibid.,31, 486–491 (1988).

    Google Scholar 

  116. C. Schudt, C. Auriga, P. Eveleigh, et al., Trends Pharmacol. Sci.,9, Suppl., 81 (1988).

    Google Scholar 

  117. C. Schudt and C. Auriga, Eur. J. Pharmacol.,145, 87–90 (1988).

    Google Scholar 

  118. C. Schudt, R. Boer, N. J. Birdsall, et al., Naunyn-Schmiedeberg's Arch. Pharmacol.,338, Suppl., 184 (1988).

    Google Scholar 

  119. C. Schudt, R. Boer, M. Eltze, et al., Eur. J. Pharmacol.,165, 87–97 (1989).

    Google Scholar 

  120. C. Schumaher, J. P. Steinberg, and J. P. Kan, ——ibid.,166, 139–149 (1989).

    Google Scholar 

  121. D. G. Spenser, L. A. A. van Rooijen, E. Horvath, et al., Trends Pharmacol. Sci.,9, Suppl., 61–68 (1988).

    Google Scholar 

  122. C. A. P. F. Su, P. Tanswell, U. Busch, et al., Eur. J. Clin. Pharmacol.,36, Suppl., 206 (1989).

    Google Scholar 

  123. R. Tacke and B. Becker, ——Tsit. [128] (1987).

    Google Scholar 

  124. R. Tacke and H. Zilch, ——Tsit. [128] (1986).

    Google Scholar 

  125. I. Takayanagi and K. Koieke, Trends Pharmacol. Sci.,9, Suppl., 80 (1988).

    Google Scholar 

  126. E. Teodori, F. Melani, and F. Gaultieri, J. Heterocycl. Chem.,23, 1487–1490 (1986).

    Google Scholar 

  127. T. W. Vickroy, W. R. Roeske, and H. I. Yamamura, J. Pharmacol. Exp. Ther.,229, 747–755 (1984).

    Google Scholar 

  128. M. Waelbroeck, M. Tastenoy, J. Camus, and J. Christophe, Br. J. Pharmacol.,98, 197–206 (1989).

    Google Scholar 

  129. J. Wange, W. R. Roeske, Brain Research,446, 155–158 (1988).

    Google Scholar 

  130. R. L. Whiting, A. D. Michel, and R. M. Eglen, Trends Pharmacol. Sci.,9, Suppl., 79 (1988).

    Google Scholar 

  131. J. M. Witkin, R. Alvarado-Garcia, L. A. Perez, and K. M. Witkin, Life Sci.,42, 2467–2473 (1988).

    Google Scholar 

  132. M. Wolf-Pflugman, G. Lambrecht, J. Wess, and E. Mutschler, Arzneim. Forsch.,39, 539–544 (1989).

    Google Scholar 

  133. P. Worms, J. P. Kon, and R. Steinberg, Naunyn-Schmiedeberg's Arch. Pharmacol.,340, 411–419 (1989).

    Google Scholar 

  134. S. H. Zorn, R. S. Duman, A. Giachetti, and R. Micheletti, J. Pharmacol. Exp. Ther.,242, 173–178 (1987).

    Google Scholar 

  135. European Patent 239, 309 (1987). Chem. Abstr.,109, No. 54780s (1988).

  136. European Patent 251, 937 (1988); ibid. Chem. Abstr.,109, No. 93036y (1988).

  137. European Patent 257, 741 (1988); ibid.,109, 73342s (1988).

  138. European Patent 259, 621 (1988); ibid. Chem. Abstr.,109, No. 6526s (1988).

  139. European Patent 323, 864 (1989); ibid. Chem. Abstr.,112, No. 77194e (1990).

  140. European Patent 326, 526 (1989); ibid. Chem. Abstr.,112, No. 76976z (1990).

  141. Ger Offen. DE 3,409,237 (1985); ibid.,104, 129934c (1986).

  142. Ger Offen. DE 3,523,002 (1987); ibid. Chem. Abstr.,106, No. 1556503j (1987).

  143. Ger Offen, DE 3,626,095 (1988); ibid. Chem. Abstr.,108, No. 204648a (1988).

  144. Ger Offen, DE 3,800,986 (1989); ibid. Chem. Abstr.,112, No. 118863t (1990).

  145. Japanese Patent 62,04.288 (1987); ibid. Chem. Abstr.,106, No. 156504k (1987).

  146. U.S.A. Pat. 4,644,033 (1987), ibid. Chem. Abstr.,106, No. 176197z (1987).

  147. S. African Pat. 6,905,933 (1970); ibid. Chem. Abstr.,73, No. 77292m (1970).

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  1. Institute of Toxicology, Russian Ministry of Health, Leningrad

    S. G. Kuznetsov, S. M. Ramsh & A. G. Zmyvalova

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Translated from Khimiko-farmatsevticheskii Zhurnal, Vol. 26, No. 1, pp. 4–17, January, 1992.

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Kuznetsov, S.G., Ramsh, S.M. & Zmyvalova, A.G. Selective muscarinic ligands (a review). Pharm Chem J 26, 1–19 (1992). https://doi.org/10.1007/BF00773189

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