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Attempt to calculate the continuous process of ion-exchange sorption of antibiotics in a multisection cone column

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Abbreviations

E(rτ):

Concentration of extracted substance in the ionite particle (in units/g of absolutely dry weight)

E0 :

Concentration of extracted substance in ionite at intake of column (in units/g of absolutely dry weight)

c(s):

Concentration of extracted substance in solution (in units/ml)

cp(s):

Concentration of extracted substance on surface of particle, its equilibrium concentration in the solution stream (in units/ml)

c0 :

Concentration of extracted substance in solution at intake of column (in units/ml)

Kc :

Coefficient of mass delivery from solution to ionite particle (in m/sec)

Dr :

Effective coefficient of internal diffusion in ionite particle (in m2/sec)

ϕ :

Coefficient of equilibrium distribution of extracted substance

deq :

Diameter of particle equivalent to a given ionite fraction (in m)

r:

Variable distance from center of particle (in m)

R:

Equivalent radius of particle (in m2)

F:

Surface of particle (in m2)

W:

Linear rate of solution supply (in m/sec)

S:

Variable distance covered by the ionite in the column (in m)

V:

Linear rate of transport of ionite particles (in m/sec)

τ :

Variable time (in sec)

τ av P/M:

Average time ionite spends in column (in h)

P:

Amount of ionite loaded in column (in g of absolutely dry weight)

M:

Discharge of ionite (in g of absolutely dry weight per h)

m:

Volumetric discharge of ionite (in ml/h/cm2)

w:

Volumetric discharge of solution (in ml/h/cm2)

η :

Degree of ionite saturation

n:

Number of operating cones

H:

Height of column

Literature cited

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 5, No. 11, pp. 24–30, November, 1971.

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Gel'perin, N.I., Klyueva, L.M. & Stremovskii, L.L. Attempt to calculate the continuous process of ion-exchange sorption of antibiotics in a multisection cone column. Pharm Chem J 5, 670–675 (1971). https://doi.org/10.1007/BF00772363

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  • DOI: https://doi.org/10.1007/BF00772363

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