Pharmaceutical Chemistry Journal

, Volume 1, Issue 4, pp 193–198 | Cite as

Basic esters and amides of substituted cinnamic acids and their analogs

  • A. P. Arendaruk
  • é. A. Gracheva
  • A. P. Skoldinov
  • D. A. Kharkevich
Article
  • 59 Downloads

Abstract

For comparative pharmacological studies, a series of quaternary salts of basic esters of cinnamic acid and of their derivatives, homologs, and analogs have been obtained. Among the compounds tested the highest curare-like activity was shown by the methiodides of theδ-dimethylaminobutyl esters of cinnamic acid and also by methoxy-and p-nitro-substituted cinnamic acids. The quaternary salts of the corresponding amides or esters containing lypophilic groups were considerably less active.

Keywords

Ester Organic Chemistry Amide Cinnamic Acid Pharmacological Study 

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Copyright information

© Consultants Bureau 1968

Authors and Affiliations

  • A. P. Arendaruk
    • 1
  • é. A. Gracheva
    • 1
  • A. P. Skoldinov
    • 1
  • D. A. Kharkevich
    • 1
  1. 1.Scientific Research Institute of Pharmacology and ChemotherapyAcademy of Medical Sciences of the USSRMoscow

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