Abstract
Chlorhexidine is widely used as a bacterial drug whose method of action has been well described in bacteria. Its fungicidal properties have been proved. We show here the effects of a sublethal dose of a preparation of digluconate of chlorhexidine on buddingCandida albicans. A fungistatic action is revealed by a decrease in the percentage of budding cells, and two main types of alterations can be observed with transmission electron microscopy (T.E.M.): a loss of cytoplasmic components and a coagulation of nucleoproteins. With scanning electron microscopy (S.E.M.), the cell walls show morphological modifications.
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Bobichon, H., Bouchet, P. Action of chlorhexidine on buddingCandida albicans: Scanning and transmission electron microscopic study. Mycopathologia 100, 27–35 (1987). https://doi.org/10.1007/BF00769565
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DOI: https://doi.org/10.1007/BF00769565