Journal of Bioenergetics and Biomembranes

, Volume 24, Issue 1, pp 91–98 | Cite as

High-conductance pathways in mitochondrial membranes

  • Oscar Moran
  • M. Catia Sorgato
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Abstract

The outer and inner membranes of mitochondria have recently been studied with the patch clamp technique. What has emerged is still an ill-defined picture for either membrane, primarily for the wide range of conductances found. Interestingly, however, a few conductances (in the range of 10–80 pS) seem to be ubiquitously distributed. Parallel studiesin situ and in reconstituted systems have allowed the assignment to distinct membrane locations of some conductances, whose physiological role is, however, not yet elucidated.

Key words

Channels intracellular membrane channels mitochondrial channels patch clamp 

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Copyright information

© Plenum Publishing Corporation 1992

Authors and Affiliations

  • Oscar Moran
    • 1
  • M. Catia Sorgato
    • 2
  1. 1.Laboratorio di NeurofisiologiaScuola Internazionale Superiore di Studi AvanzatiTriesteItaly
  2. 2.Dipartimento di Chimica BiologicaUniversitá di Padova e Centro CNR per lo Studio della Fisiologia MitocondrialePadovaItaly

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