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Use of paper chromatography in controlling the production of alkaloids from poppy pod

IV. Investigation of the effect of changes in the composition of the mobile phase on the separation of opium alkaloids

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Abstract

The effect of the ratio of toluene to isobutanol in the mobile phase on the R f values of alkaloids occurring in poppy pods is investigated. The optimum conditions for the Chromatographie separation of morphine and codeine from accompanying alkaloids are selected. This makes possible the quantitative determination of these two alkaloids in solution, in extracting alkaloids from poppy pod by an adsorption method. The necessity of using the ether-water solvent system for the quantitative determination of narcotine, papaverine, and tebaine by paper chromatography is confirmed.

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Authors and Affiliations

  1. Kharkov Pharmaceutical Chemistry Research Institute, Kharkov

    V. A. Danel'yants, S. Kh. Mushinskaya & Yu. V. Shostenko

Authors
  1. V. A. Danel'yants
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  2. S. Kh. Mushinskaya
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  3. Yu. V. Shostenko
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 2, pp. 49–53, February, 1967.

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Danel'yants, V.A., Mushinskaya, S.K. & Shostenko, Y.V. Use of paper chromatography in controlling the production of alkaloids from poppy pod. Pharm Chem J 1, 103–106 (1967). https://doi.org/10.1007/BF00768092

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  • DOI: https://doi.org/10.1007/BF00768092

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