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Syntheses in the series of methyl-2-furylketone

XII. (5-nitro-2-furyl)-substituted imidazoheterocyclic compounds with a common nitrogen atom

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Abstract

2-(5-Nitro-2-furyl)-substituted imidazo-[1,2-b]-benzothiazole and imidazo-[1,2-a]-pyridine, 6-(5-nitro-2-furyl)-substituted 3-(2-furyl)-imidazo-[1,2-b]-1,2,4-triazine, 2-methyl- and 2-(2-furyl)-imidazo-[2,1-b]-1,3,4-thiadiazoles and also 2,6-di-(5-nitro-2-furyl)-imidazo-[2,1-b]-1,3,4-thiadiazole were obtained from bromomethyl-5-nitro-2-furyl ketone and the corresponding heterocyclic amines with amidine structure. The greatest antimicrobial effect among the imidazo compounds is exhibited by 2-(5-nitro-2-furyl)-imidazo-[1,2-a]-pyridine but in most cases it has a weaker effect than furazolidone.

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Authors and Affiliations

  1. Institute of Organic Synthesis of the Academy of Sciences of the Latvian SSR, Riga

    N. O. Saldabol, S. A. Giller, L. N. Alekseeva & B. A. Brizga

Authors
  1. N. O. Saldabol
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  2. S. A. Giller
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  3. L. N. Alekseeva
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  4. B. A. Brizga
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 2, pp. 27–31, February, 1967.

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Saldabol, N.O., Giller, S.A., Alekseeva, L.N. et al. Syntheses in the series of methyl-2-furylketone. Pharm Chem J 1, 83–86 (1967). https://doi.org/10.1007/BF00768085

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  • DOI: https://doi.org/10.1007/BF00768085

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