Pharmaceutical Chemistry Journal

, Volume 1, Issue 5, pp 247–250 | Cite as

Lactams IX. A new approach to the synthesis of 5,6-dihydro-7H-pyrrolo[2,3-d]pyrimidines

  • V. G. Granik
  • R. G. Glushkov


A new method for the synthesis of derivatives of pyrrolo[2,3-d]pyrimidine has been developed, including the ethylation of 3-carboethoxy-2-pyrrolidone with triethyloxonium fluoborate and the condensation of 2-ethoxy-3-carboethoxy-1,2-dihydropyrrolidine with compounds of the general formula R-C(=NH)NH2, where R is NH2, SH, OH, SCH3, or CH3.


Organic Chemistry Pyrimidine General Formula Lactam Fluoborate 
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Copyright information

© Consultants Bureau 1968

Authors and Affiliations

  • V. G. Granik
    • 1
  • R. G. Glushkov
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Institute of Pharmaceutical ChemistryMoscow

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