Catalysis Letters

, Volume 4, Issue 2, pp 163–167 | Cite as

Regioselective epoxidation by air of sterol esters bearing several double bonds using a ruthenium porphyrin catalyst

  • Manuella Tavares
  • René Ramasseul
  • Jean-Claude Marchon


A series of sterol esters bearing varying patterns of unsaturation on the nucleus, side chain, and acyl substituent were epoxidized using trans-dioxoruthenium(VI) tetramesitylporphyrin as catalyst and air as source of oxygen. Attack at the steroid nucleus is generally favored, and a high degree of β-stereoselectivity is obtained except for conjugated 5,7 diene systems which yield a ca. 1∶1 mixture of 5,6α and 5,6β epoxides.


Oxygen Ester Physical Chemistry Steroid Catalysis 


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Copyright information

© J.C. Baltzer A.G. Scientific Publishing Company 1990

Authors and Affiliations

  • Manuella Tavares
    • 1
  • René Ramasseul
    • 1
  • Jean-Claude Marchon
    • 1
  1. 1.Laboratoire de Chimie/Chimie de Coordination (URA 1194 du CNRS), Départment de Recherche FondamentaleCentre d'Etudes Nucléaires de GrenobleGrenobleFrance

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