Skip to main content

Synthesis of metronidazole from ethylenediamine

This is a preview of subscription content, access via your institution.

Literature cited

  1. 1.

    USSR Inventor's Certificate No. 164,289; Otkrytiya, No. 15 (1964).

  2. 2.

    USSR Inventor's Certificate No. 176,912; Otkrytiya, No. 24 (1965).

  3. 3.

    USSR Inventor's Certificate No. 180,605; Otkrytiya, No. 8 (1966).

  4. 4.

    USSR Inventor's Certificate No. 201,416; Otkrytiya, No. 18 (1967).

  5. 5.

    USSR Inventor's Certificate No. 201,417; Otkrytiya, No. 18 (1967).

  6. 6.

    USSR Inventor's Certificate No. 201,418; Otkrytiya, No. 18 (1967).

  7. 7.

    P. M. Kochergin, A. M. Tsyganova, L. S. Blinova, et al., Khim. Geterotsikl. Soedin., No. 6, 875–878 (1965).

    Google Scholar 

  8. 8.

    M. D. Mashkovskii, Drugs, 9th edn. [in Russian], Part 2, Moscow (1984), p. 343.

  9. 9.

    Roumanian Patent No. 51,788 (1969); Chem. Abstr.,71, No. 124434e (1969).

  10. 10.

    French Patent No. 1,379,915 (1964); Chem. Abstr.,62, No. 9145 (1965).

  11. 11.

    G. N. Pershin, P. M. Kochergin, A. M. Tsyganova, et al., Med. Prom-st', No. 10, 12–16 (1964).

    Google Scholar 

  12. 12.

    R. Y. Fargher and F. L. Pyman, J. Chem. Soc.,115, 217 (1919).

    Google Scholar 

  13. 13.

    K. W. Kohlrauch and R. Seka, Chem. Ber.,71, 985 (1938).

    Google Scholar 

  14. 14.

    A. Ladenburg, Chem. Ber.,27, 2952–2957 (1894).

    Google Scholar 

  15. 15.

    B. Radziszewski, Chem. Ber.,15, 2706–2708 (1882).

    Google Scholar 

  16. 16.

    B. Radziszewski, Chem. Ber.,16, 487–494 (1883).

    Google Scholar 

Download references

Author information

Affiliations

Authors

Additional information

Communication 84 of the series “Studies in the series of imidazole.”

Deceased.

Translated from Khimiko-farmatsevticheskii Zhurnal, Vol. 23, No. 10, pp. 1246–1248, October, 1989.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Kraft, M.Y., Kochergin, P.M., Tsyganova, A.M. et al. Synthesis of metronidazole from ethylenediamine. Pharm Chem J 23, 861–863 (1989). https://doi.org/10.1007/BF00764821

Download citation

Keywords

  • Organic Chemistry
  • Metronidazole
  • Ethylenediamine