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Signal transduction enzymes of vertebrate photoreceptors

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Abstract

A flash of light initiates a cascade of biochemical reactions inside vertebrate photoreceptor cells, culminating in hydrolysis of intracellular cyclic GMP and hyperpolarization of the cell. The cell recovers by shutting down this cascade and resynthesizing cGMP. Many of the reactions responsible for the excitation and recovery phases of the photoresponse have been identified. Here I review some characteristics of the proteins that participate in these reactions.

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  1. Howard Hughes Medical Institute and Department of Biochemistry, University of Washington, 98195, Seattle, Washington

    J. B. Hurley

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Hurley, J.B. Signal transduction enzymes of vertebrate photoreceptors. J Bioenerg Biomembr 24, 219–226 (1992). https://doi.org/10.1007/BF00762680

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