Journal of Bioenergetics and Biomembranes

, Volume 19, Issue 6, pp 677–689 | Cite as

Selectivity of lipid-protein interactions

  • Derek Marsh


The spin label ESR and intrinsic fluorescence quenching methods of determining the selectivity of interactions of lipids with integral membrane proteins are summarized. The selectivity patterns of phospholipids, fatty acids, and steroids are reviewed for a variety of integral proteins. Where appropriate, correlations are established with biochemical assays of the effects of specific lipids on enzymatic activity and transport function.

Key words

Lipid-protein interaction lipid specificity integral protein lipid activation lipid inhibition spin label ESR fluorescence quenching 


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Copyright information

© Plenum Publishing Corporation 1987

Authors and Affiliations

  • Derek Marsh
    • 1
  1. 1.Max-Planck-Institut für biophysikalische Chemie, Abt. SpektroskopieGöttingenFRG

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