Conclusions
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1.
The limiting wear at the die hole walls in tableting a citramon preparation of given particle size distribution was equal to 20–25μ.
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2.
The wear of dies made from grade Kh12M steel was less by a factor of 3 and 2.5 respectively than that of grades 20Kh and KhVG steels.
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3.
The optimal diametral clearances between the punch caps and the dies for a diameter of 12 mm can be taken as 30–40μ, and between the punch stems and the dies 10–30μ (in order to reduce the spilling of powder).
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4.
The wear resistence of punches made from the same material as the dies is approximately double that of the dies.
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5.
The wear of the punch caps depends on the die material, while the wear of the punch stems is independent of the die material.
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Literature cited
E. E. Borzunov, The Effect of Physical Factors on the Tableting of Medicinal Powders and the Properties of the Tablets [in Russian], Dissertation, Moscow (1963).
V. I. Egorov and E. I. Vikul'eva, Med. Prom. SSSR, No. 9, 37 (1966).
E. Z. Kol'man-Ivanov and K. A. Salazkin, Tableting Machines [in Russian], Moscow (1966).
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 4, No. 3, pp. 47–49, March, 1970.
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Belousov, V.A., El'chin, N.P. Selection of press tool materials for tableting machines and a study of their wear behavior. Pharm Chem J 4, 169–171 (1970). https://doi.org/10.1007/BF00760980
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DOI: https://doi.org/10.1007/BF00760980