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A chromatographic study of certain derivatives of quinoxaline N-oxide. Part II

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Pharmaceutical Chemistry Journal Aims and scope

Conclusion

A method for the quantitative analysis of a 6-component mixture of 2,3-bis-hydroxy- and 2,3-bisacetoxymethylquinoxaline and the corresponding mono- and di-N-oxides has been developed. The method consists of paper chromatography in 3 solvent systems: formamide-benzene, formamide-chloroform, and formamide-ether and the subsequent elution of the separated substances from the paper and spectrophotometric determination of the eluate concentrations.

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Literature cited

  1. E. M. Granik and A. A. Chemerisskaya, Khim. Farmats. Zh., No. 5, 6 (1968).

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  2. L. P. Adamovich, Rational Procedures for the Combination of Analytical Processes [in Russian], Kharkov (1966).

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Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 10, pp. 41–44, October, 1968.

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Granik, E.M., Chemerisskaya, A.A. A chromatographic study of certain derivatives of quinoxaline N-oxide. Part II. Pharm Chem J 2, 569–571 (1968). https://doi.org/10.1007/BF00759639

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  • DOI: https://doi.org/10.1007/BF00759639

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