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Synthesis and investigation of compounds with potential biological activity. IV. Synthesis of pteroyl-d, L-γ-fluorglutamic acid

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Conclusion

Pteroyl-D, L-γ-fluorglutamic acid was synthesized by a triple condensation of 2,4,5-triamino-6-oxypyrimidine with α,β-dibromopropionic aldehyde and n-aminobenzoyl-D, L-γ-fluorglutamic acid in an aqueous alcoholic medium at pH 3.0–4.0.

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Literature cited

  1. J. H. Montgomery and J. R. Piper, J. Med. Chem.,8, 727 (1965).

    Google Scholar 

  2. H. J. Backer, Rec. Trav. Chim. Pays-Bas,70, 738 (1951); Chem. Abstr.,46, 9109 (1952).

    Google Scholar 

  3. J. R. Piper et al., J. Alabama Acad. Sci.,32, 267 (1961); Ref. zh. “Khimiya,” No. 24, Zh. 299 (1964).

    Google Scholar 

  4. A. S. Toocufcik and D. R. Seeger, J. Org. Chem.,26, 3351 (1961).

    Google Scholar 

  5. V. M. Berezovskii, L. I. Strel'chunas, and M. Ya. Kagan,27, 1717 (1957).

  6. L. V. Alekseeva, B. N. Lundin, and N. L. Burde, Zh. Obshch. Khim.,37, No. 1754 (1967).

  7. N. L. Burde, L. V. Alekseeva, and B. N. Lundin, ibid,38, 439 (1968).

    Google Scholar 

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Authors and Affiliations

  1. Institute of Chemistry, Ural Affiliate of the Academy of Sciences of the USSR, Sverdlovsk

    L. V. Alekseeva, N. L. Burde & B. N. Lundin

Authors
  1. L. V. Alekseeva
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  2. N. L. Burde
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  3. B. N. Lundin
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 10, pp. 30–31, October, 1968.

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Alekseeva, L.V., Burde, N.L. & Lundin, B.N. Synthesis and investigation of compounds with potential biological activity. IV. Synthesis of pteroyl-d, L-γ-fluorglutamic acid. Pharm Chem J 2, 557–558 (1968). https://doi.org/10.1007/BF00759633

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  • DOI: https://doi.org/10.1007/BF00759633

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