Conclusions
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1.
The following new S-acyl mercaptoacetic acids were obtained: phenoxyacetyl, phenacetyl,α-bromophenacetyl-,α-aminophenacetyl-, and N-phthalyl-α-aminophenacetylthioglycolic acids and some of their derivatives.
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2.
Phenoxacetyl-, phenacetyl-,α-bromophenacetyl-, and N-phthalyl-α-aminophenacetylthioglycolic acids were synthesized by reacting the appropriate acid chlorides with thioglycolic acid in an aqueous alkaline or neutral solution.
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3.
α-Aminophenacetylthioglycolic acid was obtained by acylating thioglycolic acid with N-substitutedα-aminophenylacetic acid by the combined anhydrides method.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 2, pp. 17–22, February, 1969.
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Ryabova, N.M., Rabinovich, M.S. Investigations in the synthesis of precursors and fragments of antibiotics. Pharm Chem J 3, 79–83 (1969). https://doi.org/10.1007/BF00759334
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DOI: https://doi.org/10.1007/BF00759334