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The synthesis of α-aminobenzylpenicillin (ampicillin) by acylation of 6-aminopenicillanic acid in the adsorbed state on anion exchange resin

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Literature cited

  1. F. P. Doyle, General Characteristics of Semisynthetic Penicillins, Antibiotiki (Moscow),16, No. 10 870–977 (1971).

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  7. E. M. Savitskaya, P. S. Nys, and M. S. Bulycheva, The Sorption of Zwitterlites by Ion Exchange Sorbents of Various Natures, Khim.-Farmats. Zh., No. 7, 32–38 (1969).

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  8. G. V. Samsonov, The Adsorption and Chromatography of Proteins on Ion Exchange Resins and the Process of Gel Filtration, in: Physicochemical Methods of Study, Analysis, and Fractionation of Biopolymers [in Russian], Nauka, Moscow-Leningrad (1966), pp. 187–205.

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Authors and Affiliations

  1. Leningrad Institute of Pharmaceutical Chemistry, USSR

    O. P. Kolomeitsev, V. V. Azanova & G. V. Samsonov

Authors
  1. O. P. Kolomeitsev
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  2. V. V. Azanova
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  3. G. V. Samsonov
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 9, No. 8, pp. 21–25, August, 1975.

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Kolomeitsev, O.P., Azanova, V.V. & Samsonov, G.V. The synthesis of α-aminobenzylpenicillin (ampicillin) by acylation of 6-aminopenicillanic acid in the adsorbed state on anion exchange resin. Pharm Chem J 9, 501–504 (1975). https://doi.org/10.1007/BF00758791

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  • DOI: https://doi.org/10.1007/BF00758791

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