Abstract
Conditions are described for the selective acid hydrolysis of 2-substituted-5-dimethylaminomethyleneaminopyrimidines in 0.2–2 M sulfuric acid, to give high yields of the corresponding 5-amino- and difficultly accessible 5-hydroxypyrimidines.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 801–803, June, 1990.
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Kizner, T.A., Mikhaleva, M.A. & Serebryakova, E.S. Selective acid hydrolysis of 2-substituted-5-dimethylaminomethyleneaminopyrimidines to 5-amino- and 5-hydroxypyrimidines. Chem Heterocycl Compd 26, 668–670 (1990). https://doi.org/10.1007/BF00756420
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DOI: https://doi.org/10.1007/BF00756420