Skip to main content
SpringerLink
Log in

Synthesis of N-[4-(2-naphthyl)]- and N-[4-(2-thienyl)methylaminobenzoyl]-dl-glutamic acids

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

N-[4-(2-Naphthyl)]-(IIa) and N-[4-(2-thienyl)methylaminobenzoyl]-dl-glutamic acids (IIb) have been synthesized for biological tests by the reaction of the corresponding halogen derivatives with diethyl p-aminobenzoyl-dl-glutamate (III) with subsequent hydrolysis of the esters obtained.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. S. G. Friedman, Ukr. khim. zh.,26, 356, 1960.

    Google Scholar 

  2. Y. Tong, W. Lee, and L. Goodman, J. Am. Chem. Soc.,86, 5668, 1964.

    Google Scholar 

  3. B. Dittman and A. Day, J. Med. Chem.,8, 728, 1965; C. A.,63, 13397, 1965.

    Google Scholar 

  4. B. R. Backer and J. Jordan, J. Med. Chem.,8, 35, 1965; C. A.,62, 8048, 1965.

    Google Scholar 

  5. N. A. Andreeva, The Vitamins of the Folic Acid Group [in Russian], Izd-vo AS SSSR, Moscow, 43, 1963.

    Google Scholar 

  6. N. Chapman and J. Williams, J. Chem. Soc., 5044, 1952.

  7. N. K. Kochetkov and N. V. Dudykina, ZhOKh,27, 1400, 1957.

    Google Scholar 

  8. W. Siegart and A. Day, J. Am. Chem. Soc.,79, 4391, 1957.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Kirov Ural Polytechnic Institute, Sverdlovsk

    S. L. Gurina, R. Kh. Batulina, L. V. Alekseeva & Z. V. Pushkareva

Authors
  1. S. L. Gurina
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Kh. Batulina
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. V. Alekseeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Z. V. Pushkareva
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gurina, S.L., Batulina, R.K., Alekseeva, L.V. et al. Synthesis of N-[4-(2-naphthyl)]- and N-[4-(2-thienyl)methylaminobenzoyl]-dl-glutamic acids. Chem Heterocycl Compd 4, 321 (1968). https://doi.org/10.1007/BF00755268

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00755268

Keywords

Search

Navigation