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Polyfluorinated heterocyclic compounds

VI. Electrophilic substitutions in 4,5,6,7-tetrafluoroindole

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The formylation, aminomethylation, and bromination of 4,5,6,7-tetrafluoroindole were investigated. It is shown that these reactions proceed at the 3 position and that the direction of substitution is in agreement with calculations from the Hiickel molecular orbital method.

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Authors and Affiliations

  1. Novosibirsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, USSR

    T. D. Petrova, T. I. Savchenko, L. N. Shchegoleva, T. F. Ardyukova & G. G. Yakobson

Authors
  1. T. D. Petrova
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  2. T. I. Savchenko
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  3. L. N. Shchegoleva
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  4. T. F. Ardyukova
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  5. G. G. Yakobson
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Additional information

For Communication V, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1344–1347, October, 1970.

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Petrova, T.D., Savchenko, T.I., Shchegoleva, L.N. et al. Polyfluorinated heterocyclic compounds. Chem Heterocycl Compd 6, 1251–1254 (1970). https://doi.org/10.1007/BF00755069

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  • DOI: https://doi.org/10.1007/BF00755069

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