Summary
The immunoreactivity of polyclonal antiserum to neuron-specific enolase (NSE) has been investigated. Twenty-three cases of malignant lymphoma (ML) were studied and compared with previously published reports. In our study 11 out of 23 cases showed strong or weak NSE positivity; any type of ML could be positive or negative even among B or T cell ML. This study indicated that polyclonal NSE is not a specific marker; it might be an inconstant marker of ML with no apparent correlation between reactivity and morphology or phenotype.
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Nemeth, J., Galian, A., Mikol, J. et al. Neuron-specific enolase and malignant lymphomas (23 cases). Vichows Archiv A Pathol Anat 412, 89–93 (1987). https://doi.org/10.1007/BF00750736
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DOI: https://doi.org/10.1007/BF00750736