Summary
In addition to the generec-4, other genetic factors affect the frequency of allelic recombination in thehis-3 locus. One dominant factor, designated asrec-6 +, in association withrec-4 + causes greater reduction in prototrophic frequency than obtained withrec-4 + alone. The action ofrec 6 + in crosses recessive homozygous forrec-4 is not established at the present. The effect ofrec-6 + is recognised only with onehis-3 allele but not with another. Interaction ofrec-4 + orrec-4 with other genetic factors can give approximately ten fold variation in the prototrophic frequencies obtained with a pair of alleles. It is suggested that the control of the rate of mutations during meiosis might be one of the roles of the recombination genes.
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Communicated by G. E. Magni
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Jha, K.K. Genetic factors affecting allelic recombination at the histidine-3 locus ofNeurospora crassa . Molec. Gen. Genet. 105, 30–37 (1969). https://doi.org/10.1007/BF00750313
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DOI: https://doi.org/10.1007/BF00750313