, Volume 14, Issue 3, pp 191–204 | Cite as

Modeling of cell culture processes

  • Evangelos Tziampazis
  • Athanassios Sambanis


Models of cell processes can be particularly useful in simulating, optimizing and controlling cell culture systems. Models reported in the literature are of various degrees of biological structure and mathematical complexity and describe cell growth, death, metabolism, and product formation, alone or in combination with each other. This paper reviews these modeling efforts, discusses their results, potential and limitations, and identifies areas where future modeling studies may be especially valuable.


Cell Culture Cell Growth Culture System Product Formation Modeling Effort 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Kluwer Academic Publishers 1994

Authors and Affiliations

  • Evangelos Tziampazis
    • 1
  • Athanassios Sambanis
    • 1
  1. 1.School of Chemical EngineeringGeorgia Institute of TechnologyAtlantaUSA

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