Psychopharmacology

, Volume 47, Issue 2, pp 153–155 | Cite as

The effects of pre-exposure to scopolamine on subsequent drug state discrimination

  • W. A. McKim
Animal Studies

Abstract

This experiment was done to test the prediction that preexposure to a drug state would increase the discriminability of that drug state when used as a cue in a discrimination task. Eight rats were pre-exposed to scopolamine for 20 days and 8 rats were given saline injections. The drug preexposed animals acquired a drug state discrimination more quickly than the controls. A difference was also found between the generalization gradients for each group with the pre-exposed group showing a steeper generalization gradient.

Key words

Scopolamine Dissociation Drug state discrimination Generalization 

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Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • W. A. McKim
    • 1
  1. 1.Department of PsychologyMemorial University of NewfoundlandSt. John'sCanada

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