Virchows Archiv A

, Volume 402, Issue 4, pp 459–464 | Cite as

Squamous cell carcinoma of the brain with sarcoma-like stroma

  • Felice Giangaspero
  • Valeria Manetto
  • Romano Ferracini
  • Giancarlo Piazza
Case Report


A cerebral neoplasm containing a well differentiated epidermoid cyst surrounded by islands of infiltrating squamous cell carcinoma and a pleomorphic spindle cell stroma was described. By immunoperoxidase staining all these components contained keratin. The lesion was therefore similar to malignant squamous cell lesions with sarcoma-like stroma occurring in other body sites.

Key words

Brain Carcinoma Keratin Pseudosarcoma 


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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • Felice Giangaspero
    • 1
  • Valeria Manetto
    • 2
  • Romano Ferracini
    • 2
  • Giancarlo Piazza
    • 3
  1. 1.Department of Anatomic PathologyUniversity of BolognaBolognaItaly
  2. 2.Laboratory of HistopathologyBellaria HospitalBologna
  3. 3.Division of NeurosurgeryBellaria HospitalBologna

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