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Complete1H NMR assignments of synthetic glycopeptides from the carbohydrate-protein linkage region of serglycins

  • Glycoconjugate Journal
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Abstract

We present complete1H NMR assignments for two synthetic glycopeptides representative of the carbohydrateprotein linkage region of serglycin proteoglycans. The peptides are: Ser(Galp-Xylp)-Gly-Ser-Gly-Ser(Galp-Xylp)-Gly and, Ser(Galp-Xylp)-Gly-Ser(Galp-Xylp)-Gly-Ser(Galp-Xylp)-Gly. A number of 2D NMR spectra together with a 3D NOESY-TOCSY spectrum were acquired at 600 MHz to complete the assignments of the glycopeptides dissolved in water with 40% trifluoroethanol. Preliminary analysis of the NMR data suggests folded structures for the glycopeptides.

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Authors and Affiliations

  1. Department of Biochemistry and Molecular Genetics, and Comprehensive Cancer Center, The University of Alabama at Birmingham, 35294-2041, Birmingham, AL, USA

    Ernest V. Curto, Ted T. Sakai & Michael J. Jablonsky

  2. Laboratoire de Chimie des Sucres, U.R.A. 499, U.F.R. Faculté des Sciences, Université d'Orléans, B.P. 6759, F-45067, Orléans, France

    Sandrine Rio-Anneheim, Jean-Claude Jacquinet & N. Rama Krishna

Authors
  1. Ernest V. Curto
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  2. Ted T. Sakai
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  3. Michael J. Jablonsky
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  4. Sandrine Rio-Anneheim
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  5. Jean-Claude Jacquinet
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  6. N. Rama Krishna
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Curto, E.V., Sakai, T.T., Jablonsky, M.J. et al. Complete1H NMR assignments of synthetic glycopeptides from the carbohydrate-protein linkage region of serglycins. Glycoconjugate J 13, 599–607 (1996). https://doi.org/10.1007/BF00731448

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  • DOI: https://doi.org/10.1007/BF00731448

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