Intensive Care Medicine

, Volume 14, Issue 3, pp 232–235 | Cite as

Intragastric pH measurement using a novel disposable sensor

  • M. J. Heath
  • J. D. Owen
  • S. W. Sanders
  • K. G. Tolman
Methods and Devices


An unique disposable pH sensor molded into the end of a nasogastric tube was tested in twelve healthy human volunteers. A Spearman's rank corelation coefficient (rs) of 0.90 was observed for the sensor and an indwelling miniature glass membrane electrode. The sensor did not correlate as well with aspirated stomach fluid (rs=0.68). No sensor calibration was necessary and the sensors measured ±0.1 pH in laboratory pH buffers before and after the clinical study. Both bare and shielded disposable sensors closely agreed with a shielded miniature glass electrode.

Key words

Gastric pH Disposable pH sensor Indwelling measurement Gastric fluid aspiration 


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  1. 1.
    Albin M, Friedlos J, Hillman K (1985) Continuous intragastric pH measurement in the critically ill and treatment with parenteral ranitidine. Intensive Care Med 11:295Google Scholar
  2. 2.
    Drake HF, Treasure T (1986) Continous clinical monitoring with ion-selective electrodes a feasible or desirable objective? Intensive Care Med 12:104Google Scholar
  3. 3.
    Elashoff JD (1981) Down with multiple t-tests. Gastroenterology 80:615Google Scholar
  4. 4.
    Fimmel CJ, Etienne A, Cilluffo T, von Ritter Christoph, Gasser T, Rey JP, Moscatelli PC, Sabbatini F, Pace F, Buhler HW, Bauerfeind P, Blum AL (1985) Long-term ambulatory gastric pH monitoring: validation of a new method and effect of H2-antagonists. Gastroenterology 88:1842Google Scholar
  5. 5.
    Grubb FE (1950) Sample criterion for testing outlying observations. Ann Mathe Stat 21:27Google Scholar
  6. 6.
    Harnett DL (1975) Introduction to statistic methods, second edition. Addison-Wesley, Reading, Mass, pp 540–541, A-35Google Scholar
  7. 7.
    Hastings PR, Skillman JJ, Bushnell LA, Silen W (1978, 1979) Antacid titration in the prevention of acute gastrointestinal bleeding: a controlled randomized trial in 100 critically ill patients. N Engl J Med 298:1041Google Scholar
  8. 8.
    Herbert A, Colton RR (1970) Statistical methods, 5 edn. Barnes & Noble Books, New York, NY, p 98Google Scholar
  9. 9.
    Le Gall JR, Mignon FC, Rapin M, Redjemi M, Harari A, Bader JP, Soussy CJ (1976) Acute gastro-duodenal lesions related to severe sepsis. Surg Gynaecol Obstet 142:377Google Scholar
  10. 10.
    Meiners D, Clift S, Kaminski D (1982) Evaluation of various techniques to monitor intragastric pH. Arch Surg 117:288Google Scholar
  11. 11.
    Owen JD, Brown HM (1985) Antimony and graphite hydrogen ion electrode and method of making such electrode. United States Patent No 4, 561, 963Google Scholar
  12. 12.
    Priebe HJ, Skillman JJ, Bushnell LS, Long PC, Silen W (1980) Antacid versus cimetidine in preventing acute gastrointestinal bleeding: a randomized trial in 75 critically ill patients. N Engl J Med 8:426Google Scholar
  13. 13.
    Reynolds JR, Walt RP, Hardcastle JD, Clark AG, Smart HL, Langman MJS (1986) 24-Hour intragastric pH: continous monitoring or nasogastric aspiration? Digestion 33:219Google Scholar
  14. 14.
    Sander DJ, Eng RJ, Murph AF (1985) Statistics. A fresh approach, 3 edn. McGraw-Hill, New York, NY, pp 451–454, 496Google Scholar
  15. 15.
    Stothert JC, Dellinger EP, Simonowitz DA, Schilling JA (1980) Gastric pH monitoring as a prognostic indicator for the prophylaxis of stress ulceration in the critically ill. Am J Surg 140:761Google Scholar
  16. 16.
    Walt R (1986) Twenty four hour intragastric acidity analysis for the future. Gutt 27:1Google Scholar

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • M. J. Heath
    • 1
  • J. D. Owen
    • 1
  • S. W. Sanders
    • 2
  • K. G. Tolman
    • 2
  1. 1.Zinetics Medical Technology Inc.Salt Lake CityUSA
  2. 2.Division of GastroenterologyUniversity of Utah School of MedicineSalt Lake CityUSA

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