This is a preview of subscription content, log in via an institution to check access.
References
Blin N, Stafford DW (1976) A general method for isolation of high-molecular-weight DNA from eukaryotes.Nucleic Acids Res 3: 2303–2308.
Bruening W, Bardesy N, Silverman BL et al (1992) Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development.Nat Genet 1: 144–148.
Buckler AL, Pelleltier J, Harber DA, Glaser T, Houseman DE (1991) Isolation, characterization, and expression of the murine Wilms tumor gene (WT1) during kidney development.Mol Cell Biol 11: 1707–1712.
Call KH, Glaser T, Ito CY et al (1990) Isolation and characterization of a zinc finger polypeptide gene at human chromosome 11 Wilms' tumor locus.Cell 60: 509–520.
Denys P, Malvaux P, van den Berghe H, Tanghe W, Proesmans W (1967) Association d'un syndrome anatomo-pathologique de pseudoharmaphrodisme masculin, d'une tumeur de Wilms' d'une nephropathie parenchymateuse et d'un mosaicisme XX/XY.Arch Fr Ped 24: 729–739.
Drash A, Sherman F, Hartmann WH, Blizzard RM (1970) A syndrome of pseudohermaphroditism, Wilms' tumor, hypertension, and degenerative renal disease.J Pediatr 76: 585–593.
Gessler M, Poustka A, Cavenee W, Neve RL, Orkin SH, Bruns GAP (1990) Homozygous deletion in Wilms' tumors of a zinc-finger gene identified by chromosome jumping.Nature 343: 774–778.
Harber DA, Sohn R, Buckler AR, Pelletier J, Call K, Houseman DE (1991) Alternative splicing and genomic structure of the Wilms' tumor gene WT1.Proc Natl Acad Sci USA 88: 9618–9622.
Madden SL, Cook DM, Morris JF, Gashler A, Sukhatme VP, Rauscher III. Transcriptional repression mediated by the WT1 Wilms' tumor gene product.Science 253: 1550–1553.
Manivel JC, Sibley RK, Dehner LP (1987) Complete and Incomplete Drash syndrome.Hum Pathol 18: 80–89.
Matsunaga E (1981) Genetics of Wilms' tumor.Hum Genet 57: 231–246.
Pelletier J, Bruening W, Kashtan CE et al (1991) Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome.Cell 67: 437–447.
Pritchard-Jones K, Fleming S, Davidson D et al (1990) The candidate Wilms' tumour gene is involved in genitourinary development.Nature 346: 194–197.
Sukhatme VP, Cao X, Chang LC et al (1988) A zinc finger-encoding gene coregulated withc-fos during growth and differentiation and after cellular depolarization.Cell 53: 37–43.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tsuda, M., Sakiyama, T., Kitagawa, T. et al. Molecular analysis of two Japanese cases of Denys-Drash syndrome. J Inherit Metab Dis 16, 876–880 (1993). https://doi.org/10.1007/BF00714282
Issue Date:
DOI: https://doi.org/10.1007/BF00714282