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Virchows Archiv A

, Volume 406, Issue 1, pp 1–5 | Cite as

Granular cell tumors contain myelin-associated glycoprotein

An immunohistochemical study using Leu 7 monoclonal antibody
  • J. Smolle
  • K. Konrad
  • H. Kerl
Article

Summary

An immunohistochemical staining procedure using Leu 7 (HNK-1) monoclonal antibody was used to study the distribution of myelin-associated glycoprotein in granular cell tumours. Positive reactions were noted in 10 of the 13 tumours investigated. This observation supports the concept that granular cell tumours are of Schwann cell origin.

Key words

Granular cell tumor Myelin-associated glycoprotein Leu-7 antibody 

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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • J. Smolle
    • 1
  • K. Konrad
    • 2
  • H. Kerl
    • 1
  1. 1.Department of DermatologyUniversity of GrazAustria
  2. 2.Department of Dermatology (I)University of ViennaAustria

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