Summary
A case of a Warthin tumor exhibiting sebaceous differentiation and necrotizing sialometaplasia is presented. This case suggests a common histogenesis for the Warthin tumor and sebaceous lymphadenoma. It supports the theory that necrotizing sialometaplasia is caused by factors which compromise or obstruct the blood supply to salivary gland tissues. The literature on sebaceous differentiation in Warthin tumor and on necrotizing sialometaplasia is reviewed.
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References
Arguelles MT, Viloria JBJr, Talens MC, McCrory TP (1976) Necrotizing sialometaplasia. Oral Surg Med Oral Pathol 42:86–90
Batsakis JG, Littler ER, Leahy MS (1972) Sebaceous cell lesions of the head and neck. Arch Otolaryngol 95:151–157
Bernier JL, Bhaskar SN (1958) Lymphoepithelial lesions of salivary glands. Cancer 11:1156–1179
Brannon RB, Corio RL (1979) Case for diagnosis: necrotizing sialometaplasia, left hard palate. Milit Med 144:295–296, 301
Donath K (1979) Pathohistologie des Parotisinfarktes (necrotizing sialometaplasia). Laryngol Rhinol 58:70–76
Foote FW, Frazell EL (1953) Tumors of major salivary glands. Cancer 6:1065–1133
Foote FW, Frasell EL (1954) Tumors of major salivary glands. First series atlas of tumor pathology. Armed Forces Institute of Pathology, Washington, D.C.
Geiler G (1957) Zur Pathogenese der Adenolymphome. Virchows Arch 330:172–191
Giamminola E (1975) Considerazioni istogenetiche sulla presenza di elementi sebacei in alcune neoplasie delle ghiandole salivari. Minerva Stomatol 24:23–25
Gnepp DR, Sporck FT (1980) Lymphoepithelial cyst with sebaceous differentiation (cystic sebaceous lymphadenoma). Am J Clin Pathol 74:683–687
Hamperl H (1931) Beiträge zur normalen und pathogischen Histologie menschlicher Speicheldrüsen. Sehr Mikroskop Anat Forsch 27:1–55
Lynch DP, Crago CA, Martinez MG (1979) Necrotizing Sialometaplasia: a review of the literature and report of two additional cases. Oral Surg Oral Med Oral Pathol 47:63–69
Meza-Chavez L (1949) Sebaceous glands in normal and neoplastic parotid glands — possible significance of sebaceous gland in respect to the origin of tumors of the salivary glands. Am J Pathol 25:627–645
Myers EN, Bankaci M, Barnes EL, Jr (1975) Necrotizing sialometaplasia. Arch Otolaryngol 101:628–629
Rawson AJ, Horn RC (1950) Sebaceous glands and sebaceous gland-containing tumors of the parotid salivary gland. Surgery 27:93–101
Seifert G, Bull HG, Donath K (1980) Histologic subclassification of the cystadenolymphoma of the parotid gland — analysis of 275 cases. Virchows Arch [Pathol Anat] 388:13–38
Thackray AC, Lucas RB (1974) Tumors of the major salivary glands. Atlas of tumor pathology. Fasc 10, Second series. Armed Forces Institute of Pathology, Washington, D.C.
Thackray AC, Sobin LH (1972) Histological typing of salivary gland tumors. # 7 International histological classification of tumors. World Health Organization, Geneva, Switzerland
Wasan SM (1971) Sebaceous lymphadenoma of the parotid gland. Cancer 28:1019–1022
Zechner G, Albegger KW (1973) Talgdrüsencarcinom der Parotis. Arch Klin Exp Ohr-Nas-Kehlk-Heilk 205:119–121
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Gnepp, D.R. Warthin tumor exhibiting sebaceous differentiation and necrotizing sialometaplasia. Virchows Arch. A Path. Anat. and Histol. 391, 267–273 (1981). https://doi.org/10.1007/BF00709159
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DOI: https://doi.org/10.1007/BF00709159