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Host-guest sensory system of sodium anthranilate-modifiedβ-cyclodextrin: Molecular recognition properties

  • Fumio Hamada
  • Yoshihiko Kondo
  • Kyoko Ishikawa
  • Hideaki Ito
  • Iwao Suzuki
  • Tetsuo Osa
  • Akihiko Ueno
Review Article

Abstract

Sodium anthranilate-modifiedβ-cyclodextrin (1) has been prepared as a sensor for detecting organic compounds including terpenoids and steroids.1 shows a pure monomer fluorescence whose intensity is increased or decreased upon addition of the guest species examined. In this system, the sodium anthranilate moiety acts either as a spacer, which enables the cyclodextrin to form a 1∶1 guest complex by narrowing theβ-cyclodextrin cavity or acts as a hydrophobic cap.1 shows a higher sensitivity for terpenoids than for steroids, but has a higher selective molecular recognition ablity for steroids than for terpenoids.

Key words

Modified cyclodextrin fluorescent sensory system steroids terpenoids 

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Copyright information

© Kluwer Academic Publishers 1994

Authors and Affiliations

  • Fumio Hamada
    • 1
  • Yoshihiko Kondo
    • 1
  • Kyoko Ishikawa
    • 1
  • Hideaki Ito
    • 2
  • Iwao Suzuki
    • 3
  • Tetsuo Osa
    • 3
  • Akihiko Ueno
    • 4
  1. 1.Department of Material Engineering and Applied Chemistry, Mining CollegeAkita UniversityAkitaJapan
  2. 2.Medical Course, School of MedicineAkita UniversityAkitaJapan
  3. 3.Pharmaceutical InstituteTohoku UniversitySendaiJapan
  4. 4.Department of Bioengineering, Faculty of Bioscience and BiotechnologyTokyo Institute of TechnologyYokohamaJapan

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