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Electron microprobe ultrastructural localization of aluminum in rat brain

Summary

Adult white rats were injected daily for 1 month with aluminum chloride and killed. Aluminum was identified, quantitated, and localized in the brains of these rats. The only detectable anomalies were crystals of aluminum and phosphorus in lysosomes and lipofuscin granules in the cytoplasm of neurons.

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Galle, P., Berry, JP. & Duckett, S. Electron microprobe ultrastructural localization of aluminum in rat brain. Acta Neuropathol 49, 245–247 (1980). https://doi.org/10.1007/BF00707114

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  • DOI: https://doi.org/10.1007/BF00707114

Key words

  • Aluminum
  • Brain
  • Lysosomes
  • Lipofuscin
  • Microprobe