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Structure and catalytic mechanism of methane monooxygenase and approaches to its modelling

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Abstract

The mechanisms of activation of O2 and CH4 by methane monooxygenase (MMO) are discussed. A new concept for the catalytic cycle of MMO is suggested, and approaches to its chemical modelling are considered.

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References

  1. C. Antony,The Biochemistry of Methylotrophs, Acad. Press, New York, 1982.

    Google Scholar 

  2. J. B. Vincent, G. L. Olivier-Lilley, and B. A. Averill,Chem. Revs., 1990,90, 1447.

    Google Scholar 

  3. J. Colby and H. Dalton,Biochem. J., 1978,171, 461.

    Google Scholar 

  4. B. G. Fox, W. A. Froland, J. E. Dege, and J. D. Lipscomb,J. Biol. Chem., 1989,264, 10023.

    Google Scholar 

  5. J. Green and H. Dalton,J. Biol. Chem., 1989,264, 17698.

    Google Scholar 

  6. M. R. Woodland, D. S. Patil, R. Cammack, and H. Dalton,Biochim. Biophys. Acta, 1986,873, 237.

    Google Scholar 

  7. R. C. Prince, G. N. George, J. C. Savas, S. P. Cramer, and R. N. Patel,Biochim. Biophys. Acta, 1988,952, 220.

    Google Scholar 

  8. J. G. Dewitt, J. G. Bentsen, A. C. Rosenzweig, B. Hedman, J. Green, S. Pilkington, G. C. Papaefthymiou, H. Dalton, K. O. Hodgson, and S. J. Lippard,J. Am. Chem. Soc., 1991,113, 9219.

    Google Scholar 

  9. B. G. Fox, M. P. Hendrich, K. K. Surerus, K. K. Andersson, W. A. Froland, J. D. Lipscomb, and E. Muenk,J. Am. Chem. Soc., 1993,115, 3688.

    Google Scholar 

  10. V. DeRose, K. E. Liu, S. J. Lippard, and B. Hoffman,J. Am. Chem. Soc., 1993,115, 6440.

    Google Scholar 

  11. M. P. Hendrich, B. G. Fox, K. K. Anderson, P. G. Debrunner, and J. D. Lipscomb,J. Inorg. Biochem., 1991,43, 550.

    Google Scholar 

  12. D. D. Smith and H. Dalton,Eur. J. Biochem., 1992,210, 629.

    Google Scholar 

  13. A. A. Shteinman,Dokl. Akad. Nauk, 1992,324, 617 [Dokl. Chem., 1992,324 (Engl. Transl.)].

    Google Scholar 

  14. K. J. Oberhausen, J. F. Richardson, R. J. O'Brien, R. M. Buchanan, J. K. McCusker, R. J. Webb, and D. N. Hendrickson,Inorg. Chem., 1992,31, 1123.

    Google Scholar 

  15. P. Nordlund, H. Dalton, and H. Eklund,FEBS Letters, 1992,307, 257.

    Google Scholar 

  16. A. C. Rosenzweig, C. A. Frederick, S. J. Lippard, and P. Nordlund,Nature, 1993,366, 537.

    Google Scholar 

  17. A. L. Feig and S. J. Lippard,Chem. Rev., 1994,94, 759.

    Google Scholar 

  18. A. C. Rosenzweig and S. J. Lippard,Acc. Chem. Res., 1994,27, 229.

    Google Scholar 

  19. J. Green and H. Dalton,Biochem. J., 1986,236, 155.

    Google Scholar 

  20. A. M. Khenkin and A. A. Shteinman,Kinet. Katal., 1989,30, 7 [Kinet. Catal., 1989,30 (Engl. Transl.)].

    Google Scholar 

  21. A. A. Shteinman,Izv. Akad. Nauk, Ser. Khim., 1993, 272 [Russ. Chem. Bull., 1993,42, 227 (Engl. Transl.)].

  22. A. A. Shestakov and A. E. Shilov,Zh. Obshch. Khim., 1995 (in press) [J. Gen. Chem., 1995, in press (Engl. Transl.)].

  23. H. Dalton, P. C. Wilkins, and Y. Jiang,Biochem. Soc. Trans., 1993,21, 749.

    Google Scholar 

  24. N. D. Priestley, H. G. Floss, W. A. Froland, J. D. Lipscomb, P. G. Williams, and H. Morimoto,J. Am. Chem. Soc., 1992,114, 7561.

    Google Scholar 

  25. M. J. Rataj, J. E. Kanth, and M. I. Donnally,J. Biol. Chem., 1991,266, 18684.

    Google Scholar 

  26. K. E. Liu, C. C. Johnson, M. Newcomb, and S. J. Lippard,J. Am. Chem. Soc., 1993,115, 939.

    Google Scholar 

  27. R. A. Leising, B. A. Brennan, L. Que, B. G. Fox, and E. Munck,J. Am. Chem. Soc., 1991,113, 3988.

    Google Scholar 

  28. S. W. Sam, X.-J. Tang, and J. Peisach,J. Am. Chem. Soc., 1994,116, 5250.

    Google Scholar 

  29. A. Sorokin, A. Robert, and B. Meunier,J. Am. Chem. Soc., 1993,115, 7293.

    Google Scholar 

  30. J. E. Sarneski, D. Michos, H. H. Thorp, M. Didiuk, T. Poon, J. Blewitt, G. W. Brudvig, and R. N. Crabtree,Tetr. Lett., 1991,32, 1153.

    Google Scholar 

  31. S. Bhattacharjee and R. Bhattacharyya,J. Chem. Soc.,Dalton, 1993, 1151.

  32. K. Magnus and H. Ton-Thot,J. Inorg. Biochem., 1992,47, 20.

    Google Scholar 

  33. D. M. Proserpio, R. Hoffmann, and G. Ch. Dismukes,J. Am. Chem. Soc., 1992,114, 4374.

    Google Scholar 

  34. N. Z. Muradov, A. E. Shilov, and A. A. Shteinman,React. Kin. Cat. Lett., 1975,2, 417.

    Google Scholar 

  35. J. J. Novoa, P. Constans, and M.-H. Whrang,Angew. Chem. Int. Ed., 1993,32, 588.

    Google Scholar 

  36. R. D. Bach,J. Am. Chem. Soc., 1993,115, 5768.

    Google Scholar 

  37. E. S. Rudakov,Reaktsii alkanov s okislitelyami, metallokompleksami i radikalami v rastvorakh [Reactions of Alkanes with Oxidants, Metal Complexes, and Radicals in Solutions], Naukova Dumka, Kiev, 1985 (in Russian).

    Google Scholar 

  38. J. Ling, M. Sahlin, B. M. Sjoeberg, T. M. Loehr, and J. Sanders-Loehr,J. Biol. Chem, 1994,269, 5595.

    Google Scholar 

  39. J. M. Bollinger, D. E. Edmondson, B. H. Huynh, J. Filley, J. R. Norton, and J. Stubbe,Science, 1991,253, 292.

    Google Scholar 

  40. S. K. Lee, J. C. Nesheim, and J. D. Lipscomb,J. Biol. Chem., 1993,268, 21569.

    Google Scholar 

  41. S. K. Lee, B. G. Fox, W. A. Froland, J. D. Lipscomb, and E. Munck,J. Am. Chem. Soc., 1993,115, 6450.

    Google Scholar 

  42. K. E. Liu, D. Wang, B. H. Huynh, D. E. Edmondson, A. Salifoglou, and S. J. Lippard,J. Am. Chem. Soc., 1994,116, 7465.

    Google Scholar 

  43. G. I. Panov, V. I. Sobolev, and A. I. Kharitonov,J. Mol. Catal., 1990,61, 85.

    Google Scholar 

  44. M. J. Filatov, A. G. Pelmenschikov, and G. M. Zhidomirov,J. Mol. Catal., 1993,80, 243.

    Google Scholar 

  45. Y. Zang, G. Pan, L. Que, B. G. Fox, and E. Muenck,J. Am. Chem. Soc., 1994,116, 3653.

    Google Scholar 

  46. D. M. Kurtz,Chem. Rev., 1990,90, 585.

    Google Scholar 

  47. A. A. Shteinman,Mendeleev Commun., 1992, 155.

  48. V. S. Belova, A. M. Khenkin, V. N. Postnov, V. E. Prusakov, A. E. Shilov, and M. L. Stepanova,Mendeleev Commun., 1992, 7.

  49. A. A. Shteinman,Dokl. Akad. Nauk SSSR, 1991,321, 775 [Dokl. Chem., 1991,321 (Engl. Transl.)].

    Google Scholar 

  50. R. A. Leising, J. Kim, M. A. Perez, and L. Que,J. Am. Chem. Soc., 1993,115, 9524.

    Google Scholar 

  51. S. Menage, J. M. Vincent, C. Lambeaux, G. Chottard, A. Grand, and M. Fontecave,Inorg. Chem., 1993,32, 4766.

    Google Scholar 

  52. S. Menage, J. M. Vincent, C. Lambeaux, and M. Fontecave,J. Chem. Soc., Dalton, 1994, 2081.

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Authors and Affiliations

  1. Institute of Chemical Physics in Chernogolovka, Russian Academy of Sciences, 142432, Chernogolovka, Moscow Region, Russian Federation

    A. A. Shteinman

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Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 6, pp. 1011–1020, June, 1995.

The author is grateful to Academician A. E. Shilov for interest in this work and helpful discussions. The work was financially supported by the Russian Foundation for Basic Research (Project No. 94-03-08529), International Scientific Foundation (Grant REU000), and INTAS (Project No. 93-315).

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Shteinman, A.A. Structure and catalytic mechanism of methane monooxygenase and approaches to its modelling. Russ Chem Bull 44, 975–984 (1995). https://doi.org/10.1007/BF00707038

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